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hiv-1-infection
4 studies tagged hiv-1-infection, dated 1989-07-01 to 2011-03-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
Studies
4 studies carry this tag.
Date range
1989 to 2011
Top journals
- AIDS (London, England) 1
- AIDS research and therapy 1
- Journal of leukocyte biology 1
- Journal of neuroimmunology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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With the introduction of combination antiretroviral therapy AIDS dementia complex or HIV-associated dementia, as it was termed later, largely disappeared in clinical practice.
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HIV-1 invades the central nervous system (CNS) in the context of acute infection, persists thereafter in the absence of treatment, and leads to chronic intrathecal immunoactivation that can be measured by the macrophage activation marker, neopterin, in cerebrospinal fluid (CSF).
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Human immunodeficiency virus type 1 (HIV-1)-associated dementia is a neuroinflammatory brain disorder that is fueled by viral infection and immune activation of brain mononuclear phagocytes (MP; macrophages and microglia).
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Cytokines play an important role not only for initiation of immune reactivity but also for development of tissue injury.