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forebrain-atrophy
2 studies tagged forebrain-atrophy, dated 2013-10-28 to 2014-11-27. Bibliography: BibTeX (.bib) · RIS (.ris)
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Studies
2 studies carry this tag.
Date range
2013 to 2014
Top journals
- NeuroImage. Clinical 1
- Neurobiology of aging 1
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The brains of patients suffering from Alzheimer's disease (AD) have three classical pathological hallmarks: amyloid-beta (Aβ) plaques, tau tangles, and neurodegeneration, including that of cholinergic neurons of the basal forebrain.
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We compared accuracy of hippocampus and basal forebrain cholinergic system (BFCS) atrophy to predict cortical amyloid burden in 179 cognitively normal subjects (CN), 269 subjects with early stages of mild cognitive impairment (MCI), 136 subjects with late stages of MCI, and 86 subjects with Alzheimer's disease (AD) dementia retrieved from the Alzheimer's Disease Neuroimaging Initiative database.