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flortaucipir
4 studies tagged flortaucipir, dated 2021-02-01 to 2021-06-09. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Selecting software pipelines for change in flortaucipir SUVR: Balancing repeatability and group separation 2021-06-09
- A multicenter comparison of [18F]flortaucipir, [18F]RO948, and [18F]MK6240 tau PET tracers to detect a common target ROI for differential diagnosis 2021-05-27
- Clinical validity of increased cortical uptake of [18F]flortaucipir on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase biomarker development framework 2021-02-06
Studies
4 studies carry this tag.
Date range
2021
Top journals
- European journal of nuclear medicine and molecular imaging 2
- JAMA neurology 1
- NeuroImage 1
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Since tau PET tracers were introduced, investigators have quantified them using a wide variety of automated methods.
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The temporal meta-ROI can be used for differential diagnosis of dementia patients with [ 18 F]flortaucipir, [ 18 F]RO948, and [ 18 F]MK6240 tau PET with high accuracy, and that using very similar cut-offs of around 1.35 SUVR.
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Current literature provides partial evidence for clinical utility of [ 18 F]flortaucipir PET.
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Substantial flortaucipir accumulation in temporal regions is greatest in persons aged 65 to 85 years who were CU and had high initial Aβ PET levels, compared with those with lower Aβ levels.