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exendin-4
4 studies tagged exendin-4, dated 2014-04-24 to 2023-09-04. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Exendin-4 ameliorates tau hyperphosphorylation and cognitive impairment in type 2 diabetes through acting on Wnt/β-catenin/NeuroD1 pathway 2023-09-04
- Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy 2018-10-01
- Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4 2015-08-29
Studies
4 studies carry this tag.
Date range
2014 to 2023
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 1
- Brain : a journal of neurology 1
- Molecular medicine (Cambridge, Mass.) 1
- Regulatory peptides 1
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Our study proposes that Ex-4 alleviates tau hyperphosphorylation and cognitive dysfunction by increasing Ins2-derived brain insulin through the Wnt/β-catenin/NeuroD1 signaling in T2D. And its also show new lights on part of the progress and mechanism on treatment targets for the DE in T2D.
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Exendin-4 is a drug used to treat type 2 diabetes mellitus that has also demonstrated neuroprotective properties, and is currently being tested in clinical trials for Alzheimer's and Parkinson's diseases.
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The present data suggest shared pathologic processes between concussive and B-TBI, with end points amenable to beneficial therapeutic manipulation by Ex-4.
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Glucagon-like peptide-1 (GLP-1) is a novel treatment modality for type 2 diabetes mellitus.