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Newest in this topic

  1. Exendin-4 ameliorates tau hyperphosphorylation and cognitive impairment in type 2 diabetes through acting on Wnt/β-catenin/NeuroD1 pathway 2023-09-04
  2. Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy 2018-10-01
  3. Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4 2015-08-29

Studies

4 studies carry this tag.

Date range

2014 to 2023

Top journals

  • Alzheimer's & dementia : the journal of the Alzheimer's Association 1
  • Brain : a journal of neurology 1
  • Molecular medicine (Cambridge, Mass.) 1
  • Regulatory peptides 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Exendin-4 ameliorates tau hyperphosphorylation and cognitive impairment in type 2 diabetes through acting on Wnt/β-catenin/NeuroD1 pathway

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Molecular medicine (Cambridge, Mass.) 2023-09-04 Drug development

    Our study proposes that Ex-4 alleviates tau hyperphosphorylation and cognitive dysfunction by increasing Ins2-derived brain insulin through the Wnt/β-catenin/NeuroD1 signaling in T2D. And its also show new lights on part of the progress and mechanism on treatment targets for the DE in T2D.

  2. Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Brain : a journal of neurology 2018-10-01 Drug development

    Exendin-4 is a drug used to treat type 2 diabetes mellitus that has also demonstrated neuroprotective properties, and is currently being tested in clinical trials for Alzheimer's and Parkinson's diseases.

  3. Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2015-08-29 Drug development

    The present data suggest shared pathologic processes between concussive and B-TBI, with end points amenable to beneficial therapeutic manipulation by Ex-4.

  4. Exendin-4 promotes the membrane trafficking of the AMPA receptor GluR1 subunit and ADAM10 in the mouse neocortex

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Regulatory peptides 2014-04-24 Drug development

    Glucagon-like peptide-1 (GLP-1) is a novel treatment modality for type 2 diabetes mellitus.

All topic tags with their study counts