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estrogen
4 studies tagged estrogen, dated 1998-04-01 to 2005-12-19. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model 2005-12-19
- Estrogen and androgen protection of human neurons against intracellular amyloid beta1-42 toxicity through heat shock protein 70 2004-06-01
- The impact of gender and estrogen on striatal dopaminergic neurotoxicity 1998-05-01
Studies
4 studies carry this tag.
Date range
1998 to 2005
Top journals
- Annals of the New York Academy of Sciences 1
- Nature medicine 1
- Proceedings of the National Academy of Sciences of the United States of America 1
- The Journal of neuroscience : the official journal of the Society for Neuroscience 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Much evidence indicates that women have a higher risk of developing Alzheimer's disease (AD) than do men.
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Intracellular amyloidbeta peptide (iAbeta1-42) accumulates in the Alzheimer's disease brain before plaque and tangle formation (Gouras et al., 2000) and is extremely toxic to human neurons (Zhang et al., 2002).
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The reproductive properties of estrogen are well established, but it is now evident that this steroid hormone has substantial modulatory capabilities in nonreproductive systems.
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Alzheimer's disease (AD) is characterized by the accumulation of cerebral plaques composed of 40- and 42-amino acid beta-amyloid (Abeta) peptides, and autosomal dominant forms of AD appear to cause disease by promoting brain Abeta accumulation.