Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest in this topic

  1. Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model 2005-12-19
  2. Estrogen and androgen protection of human neurons against intracellular amyloid beta1-42 toxicity through heat shock protein 70 2004-06-01
  3. The impact of gender and estrogen on striatal dopaminergic neurotoxicity 1998-05-01

Studies

4 studies carry this tag.

Date range

1998 to 2005

Top journals

  • Annals of the New York Academy of Sciences 1
  • Nature medicine 1
  • Proceedings of the National Academy of Sciences of the United States of America 1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2005-12-19 Risk genes beyond APOE

    Much evidence indicates that women have a higher risk of developing Alzheimer's disease (AD) than do men.

  2. Estrogen and androgen protection of human neurons against intracellular amyloid beta1-42 toxicity through heat shock protein 70

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2004-06-01 Genetics

    Intracellular amyloidbeta peptide (iAbeta1-42) accumulates in the Alzheimer's disease brain before plaque and tangle formation (Gouras et al., 2000) and is extremely toxic to human neurons (Zhang et al., 2002).

  3. The impact of gender and estrogen on striatal dopaminergic neurotoxicity

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Annals of the New York Academy of Sciences 1998-05-01 Biomarkers

    The reproductive properties of estrogen are well established, but it is now evident that this steroid hormone has substantial modulatory capabilities in nonreproductive systems.

  4. Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Nature medicine 1998-04-01 Risk genes beyond APOE

    Alzheimer's disease (AD) is characterized by the accumulation of cerebral plaques composed of 40- and 42-amino acid beta-amyloid (Abeta) peptides, and autosomal dominant forms of AD appear to cause disease by promoting brain Abeta accumulation.

All topic tags with their study counts