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Home › Research › Topics › engineering

engineering

4 studies tagged engineering, dated 2010-08-16 to 2026-06-04. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Optimizing Antibody-Based Therapies for Alzheimer's Disease: From Clinical Limitations to Molecular Engineering Innovations 2026-06-04
  2. Engineering anti-amyloid antibodies with transferrin receptor targeting improves brain biodistribution and mitigates ARIA 2024-07-26
  3. Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice 2022-01-01

Studies

4 studies carry this tag.

Date range

2010 to 2026

Top journals

  • Aging and disease 1
  • Proceedings of the National Academy of Sciences of the United States of America 1
  • bioRxiv 1
  • mAbs 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Optimizing Antibody-Based Therapies for Alzheimer's Disease: From Clinical Limitations to Molecular Engineering Innovations

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Aging and disease 2026-06-04 Treatments

    Antibody-based immunotherapy represents one of the most promising disease-modifying strategies for Alzheimer's disease (AD).

  2. Engineering anti-amyloid antibodies with transferrin receptor targeting improves brain biodistribution and mitigates ARIA

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv 2024-07-26 Treatments

    Although the first generation of immunotherapies for Alzheimer’s disease (AD) are now clinically approved, amyloid-related imaging abnormalities (ARIA) remain a major safety problem for this class of drugs.

  3. Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. mAbs 2022-01-01 TREM2 and immune genetics

    Triggering receptor expressed on myeloid cells 2 (TREM2) plays a crucial role in regulating microglial functions and removal of amyloid plaques in Alzheimer's disease (AD).

  4. Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2010-08-16 Risk genes beyond APOE

    Soluble oligomeric aggregates of the amyloid-beta peptide (Abeta) have been implicated in the pathogenesis of Alzheimer's disease (AD).

All topic tags with their study counts