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Newest in this topic

  1. Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria 2009-10-15
  2. Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells 1997-09-01

Studies

2 studies carry this tag.

Date range

1997 to 2009

Top journals

  • Nature medicine 1
  • The American journal of pathology 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The American journal of pathology 2009-10-15 Risk genes beyond APOE

    Presenilin-1 (PS1) and -2 (PS2), which when mutated cause familial Alzheimer disease, have been localized to numerous compartments of the cell, including the endoplasmic reticulum, Golgi, nuclear envelope, endosomes, lysosomes, the plasma membrane, and mitochondria.

  2. Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Nature medicine 1997-09-01 Risk genes beyond APOE

    Alzheimer's disease (AD) is a neurodegenerative disorder involving the florid deposition of vascular and cerebral plaques composed chiefly of amyloid beta-peptide (A beta) derived from cleavage of the amyloid precursor protein (APP).

All topic tags with their study counts