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Newest in this topic

  1. Novel presenilin 1 and 2 double knock-out cell line for in vitro validation of PSEN1 and PSEN2 mutations 2020-02-04
  2. Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model 2009-12-01
  3. Neuronal or glial expression of human apolipoprotein e4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgenic mice 2006-01-01

Studies

3 studies carry this tag.

Date range

2006 to 2020

Top journals

  • Hippocampus 1
  • Neurobiology of disease 1
  • The American journal of pathology 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Novel presenilin 1 and 2 double knock-out cell line for in vitro validation of PSEN1 and PSEN2 mutations

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neurobiology of disease 2020-02-04 Biomarkers

    Mutations in APP (amyloid precursor protein), PSEN1 (presenilin 1) or PSEN2 (presenilin 2) are the main cause of early-onset familial forms of Alzheimer's disease (autosomal dominant AD or ADAD).

  2. Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Hippocampus 2009-12-01 Biomarkers

    Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with senile beta-amyloid (Abeta) plaques and cognitive decline.

  3. Apolipoprotein E4 (ApoE4) is associated with Alzheimer's disease by unknown mechanisms.

All topic tags with their study counts