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double
3 studies tagged double, dated 2006-01-01 to 2020-02-04. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Novel presenilin 1 and 2 double knock-out cell line for in vitro validation of PSEN1 and PSEN2 mutations 2020-02-04
- Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model 2009-12-01
- Neuronal or glial expression of human apolipoprotein e4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgenic mice 2006-01-01
Studies
3 studies carry this tag.
Date range
2006 to 2020
Top journals
- Hippocampus 1
- Neurobiology of disease 1
- The American journal of pathology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Mutations in APP (amyloid precursor protein), PSEN1 (presenilin 1) or PSEN2 (presenilin 2) are the main cause of early-onset familial forms of Alzheimer's disease (autosomal dominant AD or ADAD).
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Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with senile beta-amyloid (Abeta) plaques and cognitive decline.
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Apolipoprotein E4 (ApoE4) is associated with Alzheimer's disease by unknown mechanisms.