alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Home › Research › Topics › distinct

distinct

6 studies tagged distinct, dated 2014-03-12 to 2023-09-04. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. CSF and plasma Aβ42/40 across Alzheimer's disease continuum: comparison of two ultrasensitive Simoa® assays targeting distinct amyloid regions 2023-09-04
  2. Cognitively unimpaired individuals with a low burden of Aβ pathology have a distinct CSF biomarker profile 2021-07-27
  3. CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia 2019-12-31

Studies

6 studies carry this tag.

Date range

2014 to 2023

Top journals

  • Alzheimer's research & therapy 2
  • Brain : a journal of neurology 1
  • Clinical chemistry and laboratory medicine 1
  • Journal of Alzheimer's disease : JAD 1
  • The FEBS journal 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. CSF and plasma Aβ42/40 across Alzheimer's disease continuum: comparison of two ultrasensitive Simoa® assays targeting distinct amyloid regions

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Clinical chemistry and laboratory medicine 2023-09-04 Biomarkers

    Differences observed in technical and diagnostic performance of the two assays may depend on matrix-specific amyloid processing, suggesting that further studies should be carried to standardize amyloid ratio measurement in plasma.

  2. Cognitively unimpaired individuals with a low burden of Aβ pathology have a distinct CSF biomarker profile

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Alzheimer's research & therapy 2021-07-27 Biomarkers

    There are biologically meaningful Aβ-downstream effects in individuals with a low burden of Aβ pathology, while structural and functional changes are still subtle or absent.

  3. CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Alzheimer's research & therapy 2019-12-31 Biomarkers

    NDs share a CSF profile characterized by increased levels of CSF CHIT1, YKL-40, and GFAP, which likely reflects a common neuroinflammatory response to protein misfolding and aggregation.

  4. Serum NGAL is Associated with Distinct Plasma Amyloid-β Peptides According to the Clinical Diagnosis of Dementia in Down Syndrome

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Alzheimer's disease : JAD 2015-01-01 Biomarkers

    Serum NGAL levels are increased in DS and associated with distinct species of Aβ depending on the progression of dementia as diagnosed by baseline and follow-up clinical assessments.

  5. The coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathway

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The FEBS journal 2014-05-06 Biomarkers

    Fibrillar amyloid-β (Aβ) is the major constituent of senile plaques in the brain of patients with Alzheimer's disease (AD).

  6. Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Brain : a journal of neurology 2014-03-12 Biomarkers

    Recent studies suggest that subcortical structures, including striatum, are vulnerable to amyloid-β accumulation and other neuropathological features in familial Alzheimer's disease due to autosomal dominant mutations.

All topic tags with their study counts