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Newest in this topic

  1. Comparing tau status determined via plasma pTau181, pTau231 and [18F]MK6240 tau-PET 2022-02-06
  2. γ-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics 2020-08-24
  3. Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging 2019-01-01

Studies

4 studies carry this tag.

Date range

2017 to 2022

Top journals

  • EBioMedicine 1
  • Journal of Alzheimer's disease : JAD 1
  • The EMBO journal 1
  • The Journal of biological chemistry 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Comparing tau status determined via plasma pTau181, pTau231 and [18F]MK6240 tau-PET

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. EBioMedicine 2022-02-06 Brain scans and imaging

    The threshold for positivity was 15.085 pg/mL for plasma pTau181 and 17.652 pg/mL for plasma pTau231.

  2. γ-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The EMBO journal 2020-08-24 TREM2 and immune genetics

    Sequence variants of the microglial expressed TREM2 (triggering receptor expressed on myeloid cells 2) are a major risk factor for late onset Alzheimer's disease.

  3. Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD 2019-01-01 Brain scans and imaging

    At autopsy, individuals with Alzheimer's disease (AD) exhibit heterogeneity in the distribution of neurofibrillary tangles in neocortical and hippocampal regions.

  4. Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The Journal of biological chemistry 2017-08-08 Biomarkers

    One of the hallmarks of Alzheimer's disease is the formation of extracellular amyloid plaques that consist mainly of abnormally aggregated forms of amyloid β (Aβ) peptides.

All topic tags with their study counts