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Newest in this topic

  1. Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission 2015-06-29
  2. Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model 2015-03-19
  3. Activation of the CB2 receptor system reverses amyloid-induced memory deficiency 2012-07-12

Studies

6 studies carry this tag.

Date range

1999 to 2015

Top journals

  • Proceedings of the National Academy of Sciences of the United States of America 2
  • Brain : a journal of neurology 1
  • Molecular neurodegeneration 1
  • Neurobiology of aging 1
  • The Journal of clinical investigation 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Brain : a journal of neurology 2015-06-29 Genetics

    Defects of mitochondrial dynamics are emerging causes of neurological disease.

  2. Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Molecular neurodegeneration 2015-03-19 Biomarkers

    CD2-Associated Protein affects Aβ levels and Aβ42/Aβ40 ratio in vitro.

  3. Activation of the CB2 receptor system reverses amyloid-induced memory deficiency

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2012-07-12 Biomarkers

    Cannabinoid type 2 (CB(2)) agonists are neuroprotective and appear to play modulatory roles in neurodegenerative processes in Alzheimer's disease.

  4. Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of clinical investigation 2006-11-01 Risk genes beyond APOE

    Alzheimer's disease (AD) is characterized by progressive neurodegeneration and cerebral accumulation of the beta-amyloid peptide (Abeta), but it is unknown what makes neurons susceptible to degeneration.

  5. Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2005-12-19 Risk genes beyond APOE

    Much evidence indicates that women have a higher risk of developing Alzheimer's disease (AD) than do men.

  6. Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 1999-10-01 Risk genes beyond APOE

    Mutations in the homologous presenilin 1 (PS1) and presenilin 2 (PS2) genes cause the most common and aggressive form of familial Alzheimer's disease.

All topic tags with their study counts