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damage
5 studies tagged damage, dated 1989-01-01 to 2020-03-02. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- The clinical promise of biomarkers of synapse damage or loss in Alzheimer's disease 2020-03-02
- Role of Caspase-3-Mediated Apoptosis in Chronic Caspase-3-Cleaved Tau Accumulation and Blood-Brain Barrier Damage in the Corpus Callosum after Traumatic Brain Injury in Rats 2017-07-21
- Axonal damage markers in cerebrospinal fluid are increased in ALS 2006-03-01
Studies
5 studies carry this tag.
Date range
1989 to 2020
Top journals
- Acta neurologica Scandinavica. Supplementum 1
- Alzheimer's research & therapy 1
- Journal of neurotrauma 1
- Neurobiology of disease 1
- Neurology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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A number of emerging biomarkers are able to measure synapse injury and loss in the brain and may correlate with cognitive function in AD.
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Traumatic brain injury (TBI) may be a significant risk factor for development of neurodegenerative disorders such as chronic traumatic encephalopathy (CTE), post-traumatic epilepsy (PTE), and Alzheimer's (AD) and Parkinson's (PD) diseases.
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The authors propose that axonal damage markers in CSF may discriminate between subtypes of ALS and that they could be used as markers for therapeutic trials.
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8-hydroxy-2'-deoxyguanosine (8-OHdG) or 8-hydroxyguanosine (8-OHG), a product of oxidized DNA or RNA, is a good marker of oxidative cellular damage.
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Radicals are species containing one or more unpaired electrons.