Home › Research › Topics › community-based-cohort
community-based-cohort
4 studies tagged community-based-cohort, dated 2024-02-12 to 2026-05-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Alzheimer's disease neuropathology plasma biomarkers and cognition in midlife: a community-based cohort study 2026-05-01
- Evaluation of plasma p-tau217 for detecting amyloid pathology in a heterogeneous community-based cohort 2025-07-01
- Characterization of plasma AT(N) biomarkers among a racial and ethnically diverse community-based cohort: an HABS-HD study 2025-01-01
Studies
4 studies carry this tag.
Date range
2024 to 2026
Top journals
- Alzheimer's & dementia (New York, N. Y.) 1
- Alzheimer's & dementia : the journal of the Alzheimer's Association 1
- Alzheimer's research & therapy 1
- Lancet (London, England) 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
-
Alzheimer's disease neuropathology positivity was present in 86 (6%) participants based on p-tau217/Aβ42, 196 (15%) based on Aβ42/40, and 48 (4%) based on p-tau217, and was associated with worse performance on processing speed (standardised cognitive difference comparing Alzheimer's disease neuropathology positive to negative for Aβ42/40, p-tau217, and p-tau217/Aβ42 -0·54 to -0·25; p values 0·0001 to 0·0048) and executive function (-0·42 to -0·19; p values 0·0070 to 0·049).
-
Plasma p-tau217 is an accurate indicator of amyloid pathology in a heterogeneous cohort and is superior to other plasma biomarkers assessed.
-
Our findings indicate differential relationships between comorbidities (demographic, medical, diagnostic) across NHB, Hispanic, and NHW participants.
-
Considering renal function and age is crucial when interpreting AD biomarkers in the general aging population.