Home › Research › Topics › clinical-performance
clinical-performance
3 studies tagged clinical-performance, dated 2011-02-11 to 2025-01-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Clinical performance of the fully automated Lumipulse plasma p-tau217 assay in mild cognitive impairment and mild dementia 2025-01-01
- Clinical performance of an antibody-free assay for plasma Aβ42/Aβ40 to detect early alterations of Alzheimer's disease in individuals with subjective cognitive decline 2023-01-05
- Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI 2011-02-11
Studies
3 studies carry this tag.
Date range
2011 to 2025
Top journals
- Acta neuropathologica 1
- Alzheimer's & dementia (Amsterdam, Netherlands) 1
- Alzheimer's research & therapy 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
-
Our real-world data support the clinical use of fully automated plasma p-tau217 immunoassays, although further studies in more diverse cohorts are required.
-
This study suggests that plasma Aβ42/Aβ40, as determined by this MS-based assay, has potential value as an accurate and cost-effective tool to identify individuals in the earliest stages of AD, supporting its implementation in clinical trials, preventative strategies and clinical practice.
-
To account for the combined effects on overall precision of CSF samples (fixed effect), different laboratories and analytical runs (random effects), these data were analyzed by mixed-effects modeling with the following results: within center %CV 95% CI values (mean) of 4.0-6.0% (5.3%) for CSF Aβ(1-42); 6.4-6.8% (6.7%) for t-tau and 5.5-18.0% (10.8%) for p-tau(181) and inter-center %CV 95% CI range of 15.9-19.8% (17.9%) for Aβ(1-42), 9.6-15.2% (13.1%) for t-tau and 11.3-18.2% (14.6%) for p-tau(181).