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cholinergic-basal
2 studies tagged cholinergic-basal, dated 2007-12-01 to 2016-07-07. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer's disease patients: application of a second-generation encapsulated cell biodelivery device 2016-07-07
- Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease 2007-12-01
Studies
2 studies carry this tag.
Date range
2007 to 2016
Top journals
- Alzheimer's research & therapy 1
- Archives of neurology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The data derived from this patient cohort demonstrate the safety and tolerability of sustained NGF release by a second-generation NGF-ECB implant to the basal forebrain, with uneventful surgical implant and removal of NGF-ECB implants in a new dosing cohort of four patients with AD.
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40/100
Up-regulation of alpha7 nAChRs may signal a compensatory response to maintain basocortical cholinergic activity during AD progression.