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cells-line
3 studies tagged cells-line, dated 2014-12-20 to 2020-10-28. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Answer ALS: A Large-Scale Resource for Sporadic and Familial ALS Combining Clinical Data with Multi-Omics Data from Induced Pluripotent Cell Lines 2020-10-28
- Novel presenilin 1 and 2 double knock-out cell line for in vitro validation of PSEN1 and PSEN2 mutations 2020-02-04
- Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson's disease 2014-12-20
Studies
3 studies carry this tag.
Date range
2014 to 2020
Top journals
- BMC genomics 1
- Neurobiology of disease 1
- Research Square 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Answer ALS is a comprehensive multi-omics approach to ALS to ascertain, at a population level, the various clinical-molecular- biochemical subtypes of sporadic ALS.
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Mutations in APP (amyloid precursor protein), PSEN1 (presenilin 1) or PSEN2 (presenilin 2) are the main cause of early-onset familial forms of Alzheimer's disease (autosomal dominant AD or ADAD).
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The systems genomics approach showed consistency across different biological levels (DNA, RNA and protein concentrations).