Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest in this topic

  1. The necroptosis cell death pathway drives neurodegeneration in Alzheimer's disease 2024-06-09
  2. Intracellular amyloid toxicity induces oxytosis/ferroptosis regulated cell death 2020-10-06
  3. Activation of JNK signaling mediates amyloid-ß-dependent cell death 2011-09-14

Studies

5 studies carry this tag.

Date range

2006 to 2024

Top journals

  • Acta neuropathologica 1
  • Cell death & disease 1
  • Journal of neurochemistry 1
  • Neurobiology of disease 1
  • PloS one 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. The necroptosis cell death pathway drives neurodegeneration in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Acta neuropathologica 2024-06-09 Treatments

    Although apoptosis, pyroptosis, and ferroptosis have been implicated in AD, none fully explains the extensive neuronal loss observed in AD brains.

  2. Intracellular amyloid toxicity induces oxytosis/ferroptosis regulated cell death

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Cell death & disease 2020-10-06 Genetics

    Amyloid beta (Aβ) accumulates within neurons in the brains of early stage Alzheimer's disease (AD) patients.

  3. Activation of JNK signaling mediates amyloid-ß-dependent cell death

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PloS one 2011-09-14 Brain scans and imaging

    Our data suggests that (i) accumulation of Aß42 plaques induces JNK signaling in neurons and (ii) induction of JNK contributes to Aß42 mediated cell death.

  4. Neuroprotective effects of donepezil through inhibition of GSK-3 activity in amyloid-beta-induced neuronal cell death

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neurochemistry 2009-01-23 Treatments

    Acetylcholinesterase inhibitors (AChE-inhibitors) are used for the treatment of Alzheimer's disease.

  5. Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of disease 2006-08-17 Drug development

    Expression of the Wnt antagonist Dickkopf-1 (DKK1) is induced during neurodegenerative processes associated with Alzheimer's Disease and brain ischemia.

All topic tags with their study counts