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Newest in this topic

  1. Pyroglutamate Aβ cascade as drug target in Alzheimer's disease 2021-12-08
  2. Lycopene abrogates Aβ(1-42)-mediated neuroinflammatory cascade in an experimental model of Alzheimer's disease 2015-03-20
  3. Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade 2006-06-08

Studies

4 studies carry this tag.

Date range

2005 to 2021

Top journals

  • Archives of internal medicine 1
  • Molecular psychiatry 1
  • Neuropharmacology 1
  • The Journal of nutritional biochemistry 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Pyroglutamate Aβ cascade as drug target in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Molecular psychiatry 2021-12-08 Treatments

    One of the central aims in Alzheimer's disease (AD) research is the identification of clinically relevant drug targets.

  2. Lycopene abrogates Aβ(1-42)-mediated neuroinflammatory cascade in an experimental model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of nutritional biochemistry 2015-03-20 Treatments

    The amelioration of Aβ1-42-induced spatial learning and memory impairment by lycopene could be linked, at least in part, to the inhibition of NF-κB activity and the down-regulation of expression of neuroinflammatory cytokines, suggesting that lycopene may be a potential candidate for AD treatment.

  3. We show here that donepezil, galanathamine and tacrine, therapeutic acetylcholinesterase inhibitors currently being used for treatment of Alzheimer's disease, protect neuronal cells in a time- and concentration-dependent manner from glutamate neurotoxicity that involves apoptosis.

  4. A prescribing cascade involving cholinesterase inhibitors and anticholinergic drugs

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Archives of internal medicine 2005-04-01 Treatments

    Use of cholinesterase inhibitors is associated with an increased risk of receiving an anticholinergic drug to manage urinary incontinence.

All topic tags with their study counts