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Home › Research › Topics › ca2

ca2

3 studies tagged ca2, dated 1988-09-01 to 2013-09-18. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease 2013-09-18
  2. Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating 2008-06-01
  3. Central mammalian neurons normally resistant to glutamate toxicity are made sensitive by elevated extracellular Ca2+: toxicity is blocked by the N-methyl-D-aspartate antagonist MK-801 1988-09-01

Studies

3 studies carry this tag.

Date range

1988 to 2013

Top journals

  • Frontiers in molecular neuroscience 1
  • Neuron 1
  • Proceedings of the National Academy of Sciences of the United States of America 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in molecular neuroscience 2013-09-18 Treatments

    Alzheimer disease (AD) is a major threat of twenty-first century that is responsible for the majority of dementia in the elderly.

  2. Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuron 2008-06-01 Risk genes beyond APOE

    Mutations in presenilins (PS) are the major cause of familial Alzheimer's disease (FAD) and have been associated with calcium (Ca2+) signaling abnormalities.

  3. Central mammalian neurons normally resistant to glutamate toxicity are made sensitive by elevated extracellular Ca2+: toxicity is blocked by the N-methyl-D-aspartate antagonist MK-801

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 1988-09-01 Brain scans and imaging

    It is widely held that a glutamate-like toxin that resembles N-methyl-D-aspartate may be responsible for the death of nerve cells seen after severe neurological insults including stroke, seizures, and degenerative disorders, such as Huntington disease, Alzheimer disease, and the amyotrophic lateral sclerosis-parkinsonism-dementia complex found on Guam.

All topic tags with their study counts