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brain-proteome
4 studies tagged brain-proteome, dated 2016-12-01 to 2020-09-28. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease 2020-09-28
- 27-Plex Tandem Mass Tag Mass Spectrometry for Profiling Brain Proteome in Alzheimer's Disease 2020-05-07
- Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer's disease 2019-01-28
Studies
4 studies carry this tag.
Date range
2016 to 2020
Top journals
- Analytical chemistry 1
- Molecular brain 1
- Proteomics 1
- Scientific data 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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48/100
Alzheimer's disease (AD) is characterized by an early, asymptomatic phase (AsymAD) in which individuals exhibit amyloid-beta (Aβ) plaque accumulation in the absence of clinically detectable cognitive decline.
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38/100
Multiplexed isobaric labeling methods, such as tandem mass tags (TMT), remarkably improve the throughput of quantitative mass spectrometry.
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41/100
Mitochondrial dysfunction is a key feature in both aging and neurodegenerative diseases including Alzheimer's disease (AD), but the molecular signature that distinguishes pathological changes in the AD from healthy aging in the brain mitochondria remain poorly understood.
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Despite a key role of amyloid-beta (Aβ) in Alzheimer's disease (AD), mechanisms that link Aβ plaques to tau neurofibrillary tangles and cognitive decline still remain poorly understood.