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brain-protein
3 studies tagged brain-protein, dated 2006-10-20 to 2009-06-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer's disease: Role of lipid peroxidation in Alzheimer's disease pathogenesis 2009-06-01
- Redox proteomics identification of oxidatively modified brain proteins in inherited Alzheimer's disease: an initial assessment 2006-12-01
- Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease 2006-10-20
Studies
3 studies carry this tag.
Date range
2006 to 2009
Top journals
- Journal of Alzheimer's disease : JAD 1
- Neurobiology of aging 1
- Proteomics. Clinical applications 1
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Numerous studies have shown that neuronal lipids are highly susceptible to oxidative stress including in those brain areas directly involved in the neurodegenerative process of Alzheimer's disease (AD).
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These initial results suggest that oxidatively modified proteins are important common features in both familial and sporadic AD.
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Aging canines develop cognitive dysfunction and neuropathology similar to those seen in humans, and the use of antioxidants results in reductions in oxidative damage and in improvement in cognitive function in this canine model of human aging.