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blood-based-biomarkers
11 studies tagged blood-based-biomarkers, dated 2015-05-11 to 2025-01-10. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Association and multimodal model of retinal and blood-based biomarkers for detection of preclinical Alzheimer's disease 2025-01-10
- The impact of exercise on blood-based biomarkers of Alzheimer's disease in cognitively unimpaired older adults 2024-03-15
- A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings 2024-03-14
Studies
11 studies carry this tag.
Date range
2015 to 2025
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 3
- Alzheimer's research & therapy 1
- Frontiers in neurology 1
- GeroScience 1
- JAR life 1
9 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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A subgroup cohort of 57 eyes from 32 participants with recent Aβ positron emission tomography (PET) results, comprising 18 preclinical patients (Aβ PET + ve, 32 eyes) and 14 controls (Aβ PET -ve, 25 eyes) with a mean age of 69 vs. 66, p = 0.06, was included for the assessment of a multimodal model to distinguish between the two groups.
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Physical activity is a promising preventative strategy for Alzheimer's disease: it is associated with lower dementia risk, better cognition, greater brain volume and lower brain beta-amyloid.
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Blood-based biomarkers for screening may guide tau positrion emissition tomography (PET) scan referrals to optimize prognostic evaluation in Alzheimer's disease.
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Blood-based biomarkers of AD/ADRD are influenced by common demographic and clinical characteristics.
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Our findings suggest that mid-life serum AD biomarkers could be associated with accelerated cognitive decline from mid- to late life in women.
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Except for Aβ42/40, plasma biomarkers are heritable.
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53/100
N-glycosylation has been identified as a critical attribute maintaining the beneficial effects of autoreactive Aβ antibodies.
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Various lifestyle and health factors, including education and inflammation, were associated with longitudinal changes of neurodegenerative and AD biomarker levels in midlife.
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Alzheimer's Disease (AD) is the most common form of dementia, characterised by extracellular amyloid deposition as plaques and intracellular neurofibrillary tangles of tau protein.
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These findings suggest that a simple blood-based signature not only provides estimates of NAB but also predicts cognitive decline and disease progression, identifying individuals at risk of progressing toward AD at the prodromal and preclinical stages.
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The diagnosis of dementia is challenging and early stages are rarely detected limiting the possibilities for early intervention.