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Home › Research › Topics › blocks

blocks

2 studies tagged blocks, dated 2002-07-01 to 2016-02-29. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation 2016-02-29
  2. A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish 2002-07-01

Studies

2 studies carry this tag.

Date range

2002 to 2016

Top journals

  • EMBO reports 1
  • Human molecular genetics 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Human molecular genetics 2016-02-29 Genetics

    The expansion of the GGGGCC hexanucleotide repeat in the non-coding region of the Chromosome 9 open-reading frame 72 (C9orf72) gene is the most common genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).

  2. A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. EMBO reports 2002-07-01 Risk genes beyond APOE

    Inhibition of amyloid beta-peptide (Abeta) production by blocking gamma-secretase activity is at present one of the most promising therapeutic strategies to slow progression of Alzheimer's disease pathology. gamma-secretase inhibitors apparently block Abeta generation via interference with presenilin (PS) function.

All topic tags with their study counts