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biomarkers-candidate
3 studies tagged biomarkers-candidate, dated 2010-11-25 to 2018-12-08. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer's disease 2018-12-08
- Two novel blood-based biomarker candidates measuring degradation of tau are associated with dementia: A prospective study 2018-04-11
- Proteomics of human cerebrospinal fluid: discovery and verification of biomarker candidates in neurodegenerative diseases using quantitative proteomics 2010-11-25
Studies
3 studies carry this tag.
Date range
2010 to 2018
Top journals
- Alzheimer's research & therapy 1
- Journal of proteomics 1
- PloS one 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The measurement of plasma Aβ peptides with an immunological assay can be improved by preconcentration via immunoprecipitation with an antibody against the Aβ amino-terminus and elution of the captured peptides by heating in a mild detergent-containing buffer.
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Measurement of tau in serum is feasible.
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There is an urgent need for novel biomarkers that can be used to improve the diagnosis, predict the disease progression, improve our understanding of the pathology or serve as therapeutic targets for neurodegenerative diseases.