av-1451

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1. 55/100

   Longitudinal and cross-sectional structural magnetic resonance imaging correlates of AV-1451 uptake

   ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Neurobiology of aging · 2018-02-09 · Brain scans and imaging

   We examined the relationship between in vivo estimates of tau deposition as measured by 18 F-AV-1451 tau positron emission tomography imaging and cross-sectional cortical thickness, as well as rates of antecedent cortical thinning measured from magnetic resonance imaging in individuals with and without evidence of cerebral amyloid in 63 participants from the Alzheimer's Disease Neuroimaging Initiative study, including 32 cognitively normal individuals (mean age 74 years), 27 patients with mild cognitive impairment (mean age 76.8 years), and 4 patients diagnosed with Alzheimer's disease (mean age 80 years).

   • Brain Scans
2. 43/100

   [18 F]AV-1451 clustering of entorhinal and cortical uptake in Alzheimer's disease

   ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Annals of neurology · 2018-02-06 · Brain scans and imaging

   This study demonstrates considerable variability in [ 18 F]AV-1451 tau-PET uptake in AD, but shows that a straightforward clustering based on entorhinal and cortical uptake maps well onto age and clinical presentation in AD.

   • Brain Scans
3. 38/100

   Regional Distribution, Asymmetry, and Clinical Correlates of Tau Uptake on [18F]AV-1451 PET in Atypical Alzheimer's Disease

   ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD · 2018-01-01 · Brain scans and imaging

   Tau deposition is closely related to clinical presentation in atypical AD with age playing a role in determining the degree of cortical tau deposition.

   • Brain Scans
4. 57/100

   [18F]AV-1451 binding in vivo mirrors the expected distribution of TDP-43 pathology in the semantic variant of primary progressive aphasia

   ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Journal of neurology, neurosurgery, and psychiatry · 2017-09-14 · Brain scans and imaging

   [ 18 F]AV-1451 binds in vivo regions that are likely to contain TDP-43 and not significant tau pathology.

   • Brain Biology
   • Brain Scans
   • Other Dementias

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