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automated-platform
7 studies tagged automated-platform, dated 2021-03-04 to 2025-04-09. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Plasma phospho-tau217 for Alzheimer's disease diagnosis in primary and secondary care using a fully automated platform 2025-04-09
- Diagnostic performance of plasma p-tau217 in a memory clinic cohort using the Lumipulse automated platform 2025-03-27
- Blood biomarkers for Alzheimer's disease with the Lumipulse automated platform: Age-effect and clinical value interpretation 2024-10-22
Studies
7 studies carry this tag.
Date range
2021 to 2025
Top journals
- Alzheimer's research & therapy 2
- Clinica chimica acta; international journal of clinical chemistry 1
- Frontiers in aging neuroscience 1
- Nature medicine 1
- Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 1
6 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Global implementation of blood tests for Alzheimer's disease (AD) would be facilitated by easily scalable, cost-effective and accurate tests.
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Plasma p-tau217 shows excellent results for detecting amyloid pathology at brain level in a clinical setting with an AUC of 0.95.
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The specific context of use might be considered to define the cut-offs of blood biomarkers of neurodegenerative diseases.
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Cerebrospinal fluid (CSF) core biomarkers of Alzheimer's disease (AD), including amyloid peptide beta-42 (Aβ42), Aβ42/40 ratio, and phosphorylated tau (pTau), are precious tools for supporting AD diagnosis.
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Plasma biomarkers of AD using the automated Lumipulse platform show good diagnostic performance in detecting Alzheimer's pathology in cognitively unimpaired subjects.
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Plasma Aβ42 and Aβ40 are critically influenced by kidney function; however, their ratio is advantageously spared from this effect.
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Manual ELISA assays are the most commonly used methods for quantification of biomarkers; however, they often show inter- and intra-laboratory variability that limits their wide use.