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atn
4 studies tagged atn, dated 2022-03-21 to 2023-07-26. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies 2023-07-26
- Alzheimer's disease diagnostic accuracy by fluid and neuroimaging ATN framework 2023-07-12
- Head-to-head comparison of plasma and PET imaging ATN markers in subjects with cognitive complaints 2023-06-29
Studies
4 studies carry this tag.
Date range
2022 to 2023
Top journals
- CNS neuroscience & therapeutics 1
- Molecular psychiatry 1
- Nature communications 1
- Translational neurodegeneration 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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β-amyloid (Aβ) and tau aggregation as well as neuronal injury and atrophy (ATN) are the major hallmarks of Alzheimer's disease (AD), and biomarkers for these hallmarks have been linked to neuroinflammation.
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Our findings suggest that plasma, CSF, and neuroimaging biomarkers differ considerably within the ATN framework; the most accurate target biomarkers for diagnosing AD were the CSF-A, neuroimaging-T, and neuroimaging-N within each ATN modality.
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55/100
Plasma p-tau181, as well as 18 F-florbetapir and 18 F-Florzolotau PET imaging can be considered as interchangeable biomarkers in the assessment of Aβ status in symptomatic stages of AD. 18 F-Florzolotau and 18 F-FDG PET imaging could serve as biomarkers for the severity of cognitive impairment.
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Alzheimer's disease (AD) is defined by amyloid (A) and tau (T) pathologies, with T better correlated to neurodegeneration (N).