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Newest in this topic

  1. Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques 2020-11-10
  2. Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites 2017-08-08
  3. Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis 2007-04-01

Studies

3 studies carry this tag.

Date range

2007 to 2020

Top journals

  • Molecular neurodegeneration 1
  • The Journal of biological chemistry 1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecular neurodegeneration 2020-11-10 TREM2 and immune genetics

    To evaluate whether the mouse model-derived results translate to human patients, the effects of diabetic phenotype on microglial pathology were assessed in cortical biopsies of idiopathic normal pressure hydrocephalus (iNPH) patients encompassing β-amyloid pathology.

  2. Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The Journal of biological chemistry 2017-08-08 Biomarkers

    One of the hallmarks of Alzheimer's disease is the formation of extracellular amyloid plaques that consist mainly of abnormally aggregated forms of amyloid β (Aβ) peptides.

  3. Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2007-04-01 Risk genes beyond APOE

    Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) (beta-secretase) initiates generation of beta-amyloid (Abeta), which plays an early role in Alzheimer's disease (AD).

All topic tags with their study counts