alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Home › Research › Topics › app-gene

app-gene

3 studies tagged app-gene, dated 2009-03-01 to 2017-04-17. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Evaluation of the Expression of Amyloid Precursor Protein and the Ratio of Secreted Amyloid Beta 42 to Amyloid Beta 40 in SH-SY5Y Cells Stably Transfected with Wild-Type, Single-Mutant and Double-Mutant Forms of the APP Gene for the Study of Alzheimer's Disease Pathology 2017-04-17
  2. Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains 2015-02-04
  3. A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis 2009-03-01

Studies

3 studies carry this tag.

Date range

2009 to 2017

Top journals

  • Applied biochemistry and biotechnology 1
  • Science (New York, N.Y.) 1
  • eLife 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Evaluation of the Expression of Amyloid Precursor Protein and the Ratio of Secreted Amyloid Beta 42 to Amyloid Beta 40 in SH-SY5Y Cells Stably Transfected with Wild-Type, Single-Mutant and Double-Mutant Forms of the APP Gene for the Study of Alzheimer's Disease Pathology

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Applied biochemistry and biotechnology 2017-04-17 Biomarkers

    Neuroblastoma cell lines such as SH-SY5Y are the most frequently utilized models in neurodegenerative research, and their use has advanced the understanding of the pathology of neurodegeneration over the past few decades.

  2. Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. eLife 2015-02-04 Genetics

    Previous reports have shown that individual neurons of the brain can display somatic genomic mosaicism of unknown function.

  3. A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Science (New York, N.Y.) 2009-03-01 Risk genes beyond APOE

    beta-Amyloid precursor protein (APP) mutations cause familial Alzheimer's disease with nearly complete penetrance.

All topic tags with their study counts