antihypertensive

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

1. 84/100

   Use of Antihypertensives, Blood Pressure, and Estimated Risk of Dementia in Late Life: An Individual Participant Data Meta-Analysis

   ✓ Peer-reviewed alzhub usefulness score 84 out of 100. JAMA network open · 2023-09-05 · Drug development

   This individual patient data meta-analysis of longitudinal cohort studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life.

   • Risk Factors
2. 81/100

   Investigation of antihypertensive class, dementia, and cognitive decline: A meta-analysis

   ✓ Peer-reviewed alzhub usefulness score 81 out of 100. Neurology · 2019-12-11 · Drug development

   Our findings, drawn from the current evidence base, support clinical freedom in the selection of antihypertensive regimens to achieve blood pressure goals.

   • Risk Factors
3. 45/100

   Antihypertensive agents and risk of Parkinson's disease: a nationwide cohort study

   ✓ Peer-reviewed alzhub usefulness score 45 out of 100. PloS one · 2014-06-09 · Drug development

   Our study suggests centrally-acting dihydropyridine CCB use and high cumulative doses of ACEIs and ARBs may associate with a decreased incidence of PD in hypertensive patients.

   • Treatments
   • Other Dementias
   • Risk Factors
4. 36/100

   Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier

   ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Molecular medicine (Cambridge, Mass.) · 2010-12-17 · Drug development

   Several large population-based or clinical trial studies have suggested that certain dihydropyridine (DHP) L-type calcium channel blockers (CCBs) used for the treatment of hypertension may confer protection against the development of Alzheimer disease (AD).

   • Brain Biology
   • Treatments
5. 36/100

   Antihypertensive and neuroprotective activities of rhynchophylline: the role of rhynchophylline in neurotransmission and ion channel activity

   ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of ethnopharmacology · 2010-08-22 · Drug development

   Rhynchophylline was the main constituent of several components identified from Uncaria species.

   • Treatments
6. 36/100

   Antihypertensive and neuroprotective effects of astaxanthin in experimental animals

   ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biological & pharmaceutical bulletin · 2005-01-01 · Drug development

   Astaxanthin is a natural antioxidant carotenoid that occurs in a wide variety of living organisms.

   • Risk Factors

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