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Newest in this topic

  1. High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer's disease 2024-10-02
  2. Neutral or Detrimental Effects of TREM2 Agonist Antibodies in Preclinical Models of Alzheimer's Disease and Multiple Sclerosis 2024-07-17
  3. Fc N-glycosylation of autoreactive Aβ antibodies as a blood-based biomarker for Alzheimer's disease 2023-06-01

Studies

5 studies carry this tag.

Date range

2002 to 2024

Top journals

  • Alzheimer's & dementia : the journal of the Alzheimer's Association 1
  • Alzheimer's research & therapy 1
  • Journal of molecular biology 1
  • Proceedings of the National Academy of Sciences of the United States of America 1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Alzheimer's research & therapy 2024-10-02 Biomarkers

    This article introduces an alternative immunodiagnostic approach based on the concept of a "tauosome" - the diverse set of tau fragments present within biological fluids.

  2. Neutral or Detrimental Effects of TREM2 Agonist Antibodies in Preclinical Models of Alzheimer's Disease and Multiple Sclerosis

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2024-07-17 TREM2 and immune genetics

    Human genetics and preclinical studies have identified key contributions of TREM2 to several neurodegenerative conditions, inspiring efforts to modulate TREM2 therapeutically.

  3. Fc N-glycosylation of autoreactive Aβ antibodies as a blood-based biomarker for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2023-06-01 Biomarkers

    N-glycosylation has been identified as a critical attribute maintaining the beneficial effects of autoreactive Aβ antibodies.

  4. Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2003-02-03 Risk genes beyond APOE

    Transgenic PDAPP mice, which express a disease-linked isoform of the human amyloid precursor protein, exhibit CNS pathology that is similar to Alzheimer's disease.

  5. The intracellular antibody capture technology (IACT): towards a consensus sequence for intracellular antibodies

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of molecular biology 2002-03-01 Genetics

    We describe the application of an intracellular antibody capture technology (IACT) as a generic in vivo selection procedure for isolating intracellular antibodies or ICAbs.

All topic tags with their study counts