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Newest in this topic

  1. A Cholecystokinin Analogue Ameliorates Cognitive Deficits and Regulates Mitochondrial Dynamics via the AMPK/Drp1 Pathway in APP/PS1 Mice 2024-01-01
  2. Potential Roles of Glucagon-Like Peptide-1 and Its Analogues in Dementia Targeting Impaired Insulin Secretion and Neurodegeneration 2022-03-07
  3. Neuroprotective Effects of a GLP-2 Analogue in the MPTP Parkinson's Disease Mouse Model 2021-01-01

Studies

6 studies carry this tag.

Date range

2000 to 2024

Top journals

  • Brain research 1
  • Degenerative neurological and neuromuscular disease 1
  • Journal of Parkinson's disease 1
  • Mechanisms of ageing and development 1
  • Nature cell biology 1

6 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. A Cholecystokinin Analogue Ameliorates Cognitive Deficits and Regulates Mitochondrial Dynamics via the AMPK/Drp1 Pathway in APP/PS1 Mice

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The journal of prevention of Alzheimer's disease 2024-01-01 Drug development

    CCK analogue ameliorates cognitive deficits and regulates mitochondrial dynamics by activating the CCKB receptor and the AMPK/Drp1 pathway in AD mice.

  2. Potential Roles of Glucagon-Like Peptide-1 and Its Analogues in Dementia Targeting Impaired Insulin Secretion and Neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Degenerative neurological and neuromuscular disease 2022-03-07 Drug development

    Dementia is a chronic, irreversible condition marked by memory loss, cognitive decline, and mental instability.

  3. Neuroprotective Effects of a GLP-2 Analogue in the MPTP Parkinson's Disease Mouse Model

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of Parkinson's disease 2021-01-01 Drug development

    The present results demonstrate that Gly(2)-GLP-2 can attenuate NLRP3 inflammasome-mediated inflammation and mitochondrial damage in the substantia nigra induced by MPTP, and Gly(2)-GLP-2 shows neuroprotective effects in this PD animal model.

  4. Potential roles of Glucagon-like peptide-1 and its analogues in cognitive impairment associated with type 2 diabetes mellitus

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Mechanisms of ageing and development 2020-07-02 Drug development

    Type 2 diabetes mellitus (T2DM) is a global disease that poses a significant threat to public health.

  5. Effects of the glucagon-like polypeptide-1 analogue (Val8)GLP-1 on learning, progenitor cell proliferation and neurogenesis in the C57B/16 mouse brain

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain research 2012-07-31 Drug development

    Type 2 diabetes (T2DM) has been identified as a risk factor for Alzheimer's disease.

  6. Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nature cell biology 2000-07-01 Risk genes beyond APOE

    The beta-amyloid precursor protein (beta-APP), which is involved in the pathogenesis of Alzheimer's disease, and the Notch receptor, which is responsible for critical signalling events during development, both undergo unusual proteolysis within their transmembrane domains by unknown gamma-secretases.

All topic tags with their study counts