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Newest in this topic

  1. Evidence for Reduced Somatic T-Cell Receptor Sequence Diversity Profiles Among Midwestern Amish in an Aging Cohort Study 2026-10-18
  2. Gantenerumab reduces brain amyloid-β proteoforms: Biochemical evaluation in dominantly inherited Alzheimer disease 2026-09-29
  3. Genetic Insights Into Protective Effects of GLP-1 Receptor Agonists on Stroke and Alzheimer Disease Across Ancestries 2026-09-25

Studies

1,365 studies carry this tag.

Date range

1982 to 2026

Top journals

  • Neurology 92
  • The Journal of biological chemistry 68
  • Proceedings of the National Academy of Sciences of the United States of America 47
  • Archives of neurology 43
  • JAMA neurology 36

375 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuroscience letters 1989-08-01 Disease mechanisms

    Alzheimer disease (AD) as well as other dementing disorders are characterized by a continuous loss of neurons in cortical and subcortical areas and probably by an extensive synaptic loss.

  2. Altered expression of genes for amyloid and cytoskeletal proteins in Alzheimer cortex

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Annals of neurology 1989-04-01 Biomarkers

    Recent studies have indicated a normal gene dose for the amyloid precursor protein (APP) in Alzheimer's disease (AD).

  3. The immunohistochemical demonstration of subsequences of the precursor of the amyloid A4 protein in senile plaques in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropathology and applied neurobiology 1989-03-01 Biomarkers

    The actual presence of the predicted precursor of Alzheimer's disease amyloid A4 protein, reported by Kang et al. (1987) in the Alzheimer brain, has yet to be verified.

  4. Elevated levels of an exocrine pancreatic secretory protein in Alzheimer disease brain

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Proceedings of the National Academy of Sciences of the United States of America 1989-01-01 Down syndrome and Alzheimer's

    We identified by a monoclonal antibody-based immunoradiometric assay high concentrations of an exocrine pancreatic protein called pancreatic thread protein (PTP) in several areas of Alzheimer disease (AD) brain.

  5. The amyloid percursor protein of Alzheimer disease is expressed as a 130 kDa polypeptide in various cultured cell types

    ✓ Peer-reviewed alzhub usefulness score 37 out of 100. FEBS letters 1988-12-01 Down syndrome and Alzheimer's

    The vascular and parenchymal amyloid deposits in Alzheimer disease (AD), normal aging and Down syndrome are mainly composed of a 4 kDa polypeptide (A4), which derives from a larger precursor protein (APP).

  6. Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Proceedings of the National Academy of Sciences of the United States of America 1988-10-01 Risk genes beyond APOE

    Progressive cerebral deposition of extracellular filaments composed of the beta-amyloid protein (beta AP) is a constant feature of Alzheimer disease (AD).

  7. Glial fibrillary acidic protein immunohistochemical study of Alzheimer I & II astrogliosis in Wilson's disease

    ✓ Peer-reviewed alzhub usefulness score 30 out of 100. Acta neurologica Scandinavica 1988-10-01 Biomarkers

    This study compared the relationships of the development of both Alzheimer I & II cells to reactive astrogliosis and also their distributional patterns in the demyelinated and non-demyelinated lesions in 6 cases of Wilson's disease by the use of PAP immunohistochemical technique for glial fibrillary acidic protein (GFAP).

  8. Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Neuroscience letters 1988-09-01 Inflammation and the immune system

    Cells expressing leucocyte common antigen (LCA) as well as T-cytotoxic-suppressor (T8) and T-helper-inducer (T4) antigens were detected in significant numbers in the hippocampus and temporal cortex of Alzheimer but not normal brain tissue.

  9. Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Science 1988-04-29 Genetics

    Apolipoprotein E is a plasma protein that serves as a ligand for low density lipoprotein receptors and, through its interaction with these receptors, participates in the transport of cholesterol and other lipids among various cells of the body.

  10. Studies were undertaken to assess the extent to which messenger RNA prepared from the postmortem Alzheimer's disease (AD) brain can be used for the successful preparation of a recombinant cDNA library.

  11. Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Nature 1988-02-01 Risk genes beyond APOE

  12. Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Science 1987-02-20 Risk genes beyond APOE

    Four clones were isolated from an adult human brain complementary DNA library with an oligonucleotide probe corresponding to the first 20 amino acids of the beta peptide of brain amyloid from Alzheimer's disease.

  13. Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Science (New York, N.Y.) 1987-02-01 Down syndrome and Alzheimer's

    The amyloid beta protein has been identified as an important component of both cerebrovascular amyloid and amyloid plaques of Alzheimer's disease and Down syndrome.

  14. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Nature 1987-02-01 Disease mechanisms

    The researchers isolated and sequenced an apparently full-length complementary DNA clone coding for the A4 polypeptide.

  15. Intraneuronal aluminum accumulation in amyotrophic lateral sclerosis and Parkinsonism-dementia of Guam

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Science (New York, N.Y.) 1982-09-01 Getting a diagnosis

    Scanning electron microscopy with energy-dispersive x-ray spectrometry was used to analyze the elemental content of neurofibrillary tangle (NFT)-bearing and NFT-free neurons within the Sommer's sector (H1 region) of the hippocampus in Guamanian Chamorros with amyotrophic lateral sclerosis and parkinsonism-dementia and in neurologically normal controls.

From across this tag

9 of the 1,363 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

All topic tags with their study counts