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Newest in this topic

  1. Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice 2010-11-25
  2. Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice 2009-06-12

Studies

2 studies carry this tag.

Date range

2009 to 2010

Top journals

  • Brain research 1
  • Neurobiology of disease 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain research 2010-11-25 Drug development

    In addition to simply reducing the serum level of cholesterol, 3-hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have various pleiotrophic effects such as reducing oxidative stress, neuroinflammation, and neurotoxicity.

  2. Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of disease 2009-06-12 Drug development

    Cerebrovascular dysfunctions appear to contribute to Alzheimer's disease (AD) pathogenesis and the associated cognitive decline.

All topic tags with their study counts