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Home › Research › Topics › activation

activation

9 studies tagged activation, dated 2006-01-03 to 2022-05-07. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia 2022-05-07
  2. Attenuation of Aluminum Chloride-Induced Neuroinflammation and Caspase Activation Through the AKT/GSK-3β Pathway by Hesperidin in Wistar Rats 2018-04-23
  3. Central and peripheral markers of neurodegeneration and monocyte activation in HIV-associated neurocognitive disorders 2015-03-17

Studies

9 studies carry this tag.

Date range

2006 to 2022

Top journals

  • Neurobiology of aging 2
  • Journal of neurovirology 1
  • Molecular neurodegeneration 1
  • Neurobiology of disease 1
  • Neurotoxicity research 1

8 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Molecular neurodegeneration 2022-05-07 Genetics

    Here, we characterized microglial BIN1 expression in vitro and in vivo and ascertained microglia expressed BIN1 isoforms.

  2. Attenuation of Aluminum Chloride-Induced Neuroinflammation and Caspase Activation Through the AKT/GSK-3β Pathway by Hesperidin in Wistar Rats

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neurotoxicity research 2018-04-23 Biomarkers

    Hesperidin, a flavanoglycone abundantly present in citrus fruits, is reported to have antioxidant, anti-inflammatory, and neuroprotective properties.

  3. Central and peripheral markers of neurodegeneration and monocyte activation in HIV-associated neurocognitive disorders

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of neurovirology 2015-03-17 Biomarkers

    HIV-associated neurocognitive disorders (HAND) affect up to 50 % of HIV-infected adults, independently predict HIV morbidity/mortality, and are associated with neuronal damage and monocyte activation.

  4. Clinical relevance of specific T-cell activation in the blood and cerebrospinal fluid of patients with mild Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Neurobiology of aging 2014-08-23 Brain scans and imaging

    In Alzheimer's disease, the contribution of inflammation is still controversially discussed.

  5. Blockage of CR1 prevents activation of rodent microglia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of disease 2013-02-27 Genetics

    The importance of the complement system in Alzheimer's disease (AD) pathogenesis has been emphasized through recent genome wide association studies.

  6. Activation of the CB2 receptor system reverses amyloid-induced memory deficiency

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2012-07-12 Biomarkers

    Cannabinoid type 2 (CB(2)) agonists are neuroprotective and appear to play modulatory roles in neurodegenerative processes in Alzheimer's disease.

  7. Activation of JNK signaling mediates amyloid-ß-dependent cell death

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PloS one 2011-09-14 Brain scans and imaging

    Our data suggests that (i) accumulation of Aß42 plaques induces JNK signaling in neurons and (ii) induction of JNK contributes to Aß42 mediated cell death.

  8. Activation of caspase-6 in aging and mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The American journal of pathology 2007-04-01 Genetics

    Active caspase-6 (Csp6) and Tau cleaved by Csp6 (TauDeltaCsp6) are abundant in neuritic plaques (NPs), neuropil threads (NPTs), and neurofibrillary tangles (NFTs) in end-stage Alzheimer's disease (AD) (Guo H, Albrecht S, Bourdeau M, Petzke T, Bergeron C, LeBlanc AC: Active caspase-6 and caspase-6 cleaved Tau in neuropil threads, neuritic plaques and neurofibrillary tangles of Alzheimer's disease.

  9. Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2006-01-03 Risk genes beyond APOE

    Epidemiological evidence suggests that nonsteroidal anti-inflammatory drugs (NSAIDs) decrease the risk for Alzheimer's disease (AD).

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