abnormalities

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

1. 48/100

   In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds

   ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Nature neuroscience · 2024-12-24 · Disease mechanisms

   Tau pathology is a hallmark of several neurodegenerative diseases, including frontotemporal dementia and Alzheimer's disease.

   • Brain Biology
2. 48/100

   Abnormalities of saccadic eye movements in dementia due to Alzheimer's disease and mild cognitive impairment

   ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Aging · 2019-08-02 · Brain scans and imaging

   The findings revealed that eye-tracking can distinguish between the two forms of MCI.

   • Early Stage
3. 41/100

   Pathogenesis and neuroimaging of cerebral large and small vessel disease in type 2 diabetes: A possible link between cerebral and retinal microvascular abnormalities

   ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of diabetes investigation · 2016-08-03 · Brain scans and imaging

   Diabetes patients have more than double the risk of ischemic stroke compared with non-diabetic individuals, and its neuroimaging characteristics have important clinical implications.

   • Brain Scans
   • Risk Factors
   • Other Dementias
4. 43/100

   Saccade abnormalities in autopsy-confirmed frontotemporal lobar degeneration and Alzheimer disease

   ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Archives of neurology · 2012-04-01 · Brain scans and imaging

   Decreased visually guided saccade velocity and gain are suggestive of underlying tau pathology in FTD, with vertical saccade abnormalities most diagnostic of progressive supranuclear palsy.

   • Brain Biology
   • Other Dementias
5. 44/100

   Retinal microvascular abnormalities and subclinical magnetic resonance imaging brain infarct: a prospective study

   ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Brain : a journal of neurology · 2010-06-02 · Brain scans and imaging

   Silent brain infarct and white matter lesions are common radiological findings associated with the risk of clinical stroke and dementia; however, our understanding of their underlying pathophysiology and risk factors remains limited.

   • Brain Scans
   • Risk Factors
6. 36/100

   Sleep and circadian abnormalities in a transgenic mouse model of Alzheimer's disease: a role for cholinergic transmission

   ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuroscience · 2005-01-01 · Brain scans and imaging

   The Tg2576 mouse model of Alzheimer's disease (AD) exhibits age-dependent amyloid beta (Abeta) deposition in the brain.

   • Brain Biology
   • Lifestyle
7. 40/100

   Regional glucose metabolic abnormalities are not the result of atrophy in Alzheimer's disease

   ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Neurology · 1998-06-01 · Brain scans and imaging

   Reduced glucose metabolism measured by PET in AD is not simply an artifact due to an increase in CSF space induced by atrophy, but reflects a true metabolic reduction per gram of tissue.

   • Brain Scans

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