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52/100

✓ Peer-reviewed alzhub usefulness score 52 out of 100. Risk factors

Topic: Brain imaging, connectivity and assessment

111 out of 287 participants had hearing impairment. Compared with those with preserved hearing, hearing impaired individuals had faster rates of whole brain atrophy, and worse hearing (higher pure tone average) predicted faster rates of hippocampal atrophy. In participants with hearing impairment, faster rates of whole brain atrophy predicted greater cognitive change. All observed relationships were independent of β-amyloid deposition and white matter hyperintensity volume. Hearing loss may influence dementia risk via pathways distinct from those typically implicated in Alzheimer's and cerebrovascular disease in cognitively unimpaired older adults.

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APA 7th

Parker, T. D., Hardy, C., Keuss, S., Coath, W., Cash, D. M., Lu, K., et al. (2024). Peripheral hearing loss at age 70 predicts brain atrophy and associated cognitive change. Journal of neurology, neurosurgery, and psychiatry. https://doi.org/10.1136/jnnp-2023-333101

Vancouver

Parker TD, Hardy C, Keuss S, Coath W, Cash DM, Lu K, et al. Peripheral hearing loss at age 70 predicts brain atrophy and associated cognitive change. Journal of neurology, neurosurgery, and psychiatry. 2024. doi:10.1136/jnnp-2023-333101. PMID: 38569877.

BibTeX

@article{parker2024-38569877,
  author  = {Parker, Thomas D and Hardy, Chris and Keuss, Sarah and Coath, William and Cash, David M and Lu, Kirsty and Nicholas, Jennifer M and James, Sarah-Naomi and others},
  title   = {{Peripheral hearing loss at age 70 predicts brain atrophy and associated cognitive change}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2024},
  doi     = {10.1136/jnnp-2023-333101},
  pmid    = {38569877},
  url     = {https://doi.org/10.1136/jnnp-2023-333101}
}

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Key findings

111 out of 287 participants had hearing impairment.
Compared with those with preserved hearing, hearing impaired individuals had faster rates of whole brain atrophy, and worse hearing (higher pure tone average) predicted faster rates of hippocampal atrophy.
In participants with hearing impairment, faster rates of whole brain atrophy predicted greater cognitive change.
All observed relationships were independent of β-amyloid deposition and white matter hyperintensity volume.
Hearing loss may influence dementia risk via pathways distinct from those typically implicated in Alzheimer's and cerebrovascular disease in cognitively unimpaired older adults.

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Study details

Participants287
Evidence strengthLow

How this study scored 52/100

Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 29 of the 56 points we could judge it on, which is 52 out of 100.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Journal of neurology, neurosurgery, and psychiatry)
Journal's citation record	— / 4	No journal record from OpenAlex — left out of this score
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	4 / 5	2024 — within 3 year(s) of the newest study here
Sample size	2 / 4	287 participants
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	— / 7	No citation count (not found in OpenAlex) — left out of this score
Citations per year	— / 5	No citation count or no year — left out of this score
Impact for its field and year	— / 6	No field-weighted citation impact (OpenAlex has none yet) — left out of this score
Cited by studies here	— / 6	Not yet checked against this library's citation graph — left out of this score
Still being cited	— / 4	No yearly citation counts — left out of this score
Senior author's track record	— / 4	Senior author's record not available — left out of this score
Institution's track record	— / 3	No institution listed in OpenAlex — left out of this score
Multi-centre collaboration	— / 3	Institutions not listed — left out of this score
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 38569877)
Free to read	— / 2	Access not recorded — left out of this score
Points	29 / 56	Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 29 of the 56 points we could judge it on is 52 out of 100.
Total	52 / 100	—

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