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315 results for "driving".

Research summaries 292

Showing the best 200 of 292, 71–80, page 8 of 20. Filter these by subject, year and score in the research library →

  1. Environment, lifestyle, and cancer in womenResearch summary

    Research summaries · alzhub.org/study/environment-lifestyle-and-cancer-in-women-40277318

    … factors, with obesity driving hormonal disruptions and systemic inflammation. Physical inactivity and diets rich in animal fats increase the risk of endometrial cancer, along with air pollution and microbiome imbalances …

  2. Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal SyndromeResearch summary

    Research summaries · alzhub.org/study/evaluation-of-plasma-phosphorylated-tau217-for-differentiation-37010841

    … have revealed AD is the driving neuropathology in up to 40% of cases. This differentiates CBS from other 4-repeat tauopathy (4RT)-associated syndromes, such as progressive supranuclear palsy Richardson syndrome (PSP-RS) and …

  3. Neighborhood disadvantage and dementia incidence in a cohort of Asian American and non‐Latino White older adults in Northern CaliforniaResearch summary

    Research summaries · alzhub.org/study/neighborhood-disadvantage-and-dementia-incidence-in-a-cohort-of-asian-35388625

    … different mechanisms driving dementia incidence in these groups could inform dementia prevention efforts. Among non-Latino White older adults, living in a more disadvantaged neighborhood was linked to a slightly higher rate of …

  4. Neuroimaging and plasma biomarker differences and commonalities in Lewy body dementia subtypesResearch summary

    Research summaries · alzhub.org/study/neuroimaging-and-plasma-biomarker-differences-and-commonalities-in-40403153

    … distinct from those driving dementia. The presence of dementia in Lewy body disease was associated with poorer white matter macrostructure and may relate to pathological protein accumulation, with plasma neurofilament light and …

  5. Pathways to Racial/Ethnic Inequalities in DementiaResearch summary

    Research summaries · alzhub.org/study/pathways-to-racial-ethnic-inequalities-in-dementia-39805030

    … and unique mechanisms driving inequalities across minoritized groups, where research is lacking. This health inequality reflects structural racism, which creates and sustains racial differences in social determinants of health, …

  6. Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseasesResearch summary

    Research summaries · alzhub.org/study/shared-and-disease-specific-pathways-in-frontotemporal-dementia-and-40665052

    … in FTD) potentially driving these proteomic changes. These findings reveal distinct and shared mechanisms across NDs, highlighting potential regulatory proteins and pathways for diagnostic and therapeutic strategies in …

  7. Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditionsResearch summary

    Research summaries · alzhub.org/study/trem2-promotes-anti-inflammatory-responses-in-microglia-and-is-32959884

    … Trem2 was important for "driving a number of the genes up-regulated in the anti-inflammatory phenotype." This is laboratory and animal work and does not establish a treatment, cure or prevention for Alzheimer's disease. We have …

  8. Visual dysfunction in dementia with Lewy bodiesResearch summary

    Research summaries · alzhub.org/study/visual-dysfunction-in-dementia-with-lewy-bodies-38907811

    … visual hallucinations, driving impairment, falls, and other negative outcomes. While visual dysfunction in clinically manifest DLB is well recognized, recent work has focused on prodromal or mild cognitive impairment (MCI) due …

  9. Amyloid-β, Tau Protein, α-Synuclein, TDP-43, and FUS in Mixed Pathology: And Intrinsic Disorder to Rule Them AllResearch summary

    Research summaries · alzhub.org/study/amyloid-tau-protein-synuclein-tdp-43-and-fus-in-mixed-pathology-and-42074305

    … proteins, (2) mechanisms driving mixed neuropathology, (3) therapeutic implications of disorder-driven interactions, and (4) key unresolved questions shaping future research. By framing neurodegeneration as a network of …

  10. Blood-Based Analysis of Different Tau Variants in Patients With Multiple Traumatic InjuriesResearch summary

    Research summaries · alzhub.org/study/blood-based-analysis-of-different-tau-variants-in-patients-with-41665901

    … biological processes driving tau release. This study measured phosphorylated and nonphosphorylated tau variants in the blood of patients with multiple traumatic injuries to better understand what drives tau release into the …

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