28,580 Alzheimer's and dementia studies in plain English, each scored out of 100.
Comparative effectiveness of behavioral interventions to mitigate the impacts of degeneration-based cognitive decline is not well understood. 4 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
The combined advances of a new, protease-resistant SDF-1 and nanofiber-mediated delivery promoted recruitment of stem cells and improved cardiac function after myocardial infarction. 1 key finding →
Evidence: high
Full summary, score breakdown and related studies → Original source
Twenty-two patients with Parkinson's disease drawn from a community-based study were followed prospectively until their deaths. 2 key findings →
Participants: 18 Evidence: low
Full summary, score breakdown and related studies → Original source
Visual hallucinations are common symptoms in Parkinson's disease and are most likely of multifactorial origin. 5 key findings →
Participants: 30 Evidence: low
Full summary, score breakdown and related studies → Original source
We assessed the validity and interrater reliability of neurologists who, using four different sets of previously published criteria for the clinical diagnosis of progressive supranuclear palsy (PSP), also called Steele-Richardson-Olszewski syndrome, rated 105 autopsy-proven cases of PSP (n = 24), Lewy body disease (n = 29), corticobasal ganglionic degeneration (n = 10), postencephalitic parkinsonism (n = 7), multiple system atrophy (n = 16), Pick's disease (n = 7), and other parkinsonian or dementia disorders (n = 12). 2 key findings →
Participants: 24 Evidence: low
Full summary, score breakdown and related studies → Original source
Semantic dementia is a syndrome of progressive deterioration in semantic memory (knowledge of objects, people, concepts and words). 1 key finding →
Participants: 13 Evidence: low
Full summary, score breakdown and related studies → Original source
Many older elective orthopedic surgical patients have probable cognitive impairment preoperatively. 4 key findings →
Participants: 211 Evidence: low
Full summary, score breakdown and related studies → Original source
Delirium is a severe, acute neuropsychiatric syndrome that is highly prevalent in acute hospital populations. 4 key findings →
Participants: 1,885 Evidence: low
Full summary, score breakdown and related studies → Original source
Data synthesis Eszopiclone, zolpidem, and suvorexant improved short-term global and sleep outcomes compared with placebo, although absolute effect sizes were small (low- to moderate-strength evidence). 4 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
These findings indicate that the use of antipsychotic agents and sedatives can affect the natural course of Alzheimer disease. 5 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source
To assess the occurrence and related features of motor vehicle crashes in patients with dementia of the Alzheimer type (DAT) we studied 30 patients who had been followed longitudinally and 20 healthy age-matched control subjects. 2 key findings →
Participants: 30 Evidence: low
Full summary, score breakdown and related studies → Original source
Circadian rhythms in elderly patients with severe dementia and behavioral disorders such as wandering, agitation and/or delirium were examined. 1 key finding →
Participants: 24 Evidence: low
Full summary, score breakdown and related studies → Original source
There is a consistent pattern of vulnerability to LB formation across subcortical, paralimbic, and neocortical structures that is similar for DLB cases with or without concomitant AD. 4 key findings →
Participants: 25 Evidence: low
Full summary, score breakdown and related studies → Original source
The difficulty in differentiating progressive supranuclear palsy (PSP, also called Steele-Richardson-Olszewski syndrome) from other related disorders was the incentive for a study to determine the clinical features that best distinguish PSP. 5 key findings →
Participants: 24 Evidence: low
Full summary, score breakdown and related studies → Original source
Performance on a brief cognitive screen on admission was strongly related to subsequent change in function. 2 key findings →
Participants: 2,557 Evidence: low
Full summary, score breakdown and related studies → Original source
Diffuse aspiration bronchiolitis (DAB) is a new term that we proposed to define a clinical entity that is characterized by a chronic inflammation of bronchioles caused by recurrent aspiration of foreign particles. 3 key findings →
Participants: 31 Evidence: low
Full summary, score breakdown and related studies → Original source
The case story of a 47-year-old man with advanced rectal carcinoma illustrates the professional services and care system strategies available to help clinicians serve patients coming to the end of life. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The results of our study contribute to a better understanding of the factors hindering GPs in initiating ACP. 2 key findings →
Participants: 36 Evidence: low
Full summary, score breakdown and related studies → Original source
In interviews PWD were able to indicate their treatment preferences across all three scenarios. 2 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Most people in Germany die in institutions; the most common place of death is still the hospital, where more than half of all deaths take place. 2 key findings →
Participants: 24 Evidence: low
Full summary, score breakdown and related studies → Original source
This qualitative evaluation of ACP in early dementia has encouragingly positive results which support the wider application of the intervention in memory services and community mental health teams. 2 key findings →
Participants: 12 Evidence: low
Full summary, score breakdown and related studies → Original source
Cessation of life-support treatment is an appropriate option for situations in which the burdens of therapy substantially outweigh the benefits. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Prevalence of ACPs and formal authorization of a legal representative was low among the deceased NH residents in Flanders, Belgium. 2 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Our comparative study of psychometric properties of instruments allows for informed selection of QOC and QOD measures for LTC residents with dementia. 1 key finding →
Participants: 70 Evidence: low
Full summary, score breakdown and related studies → Original source
Study results highlight a critical need for better prognostic counseling and education for persons and families living with DLB. 4 key findings →
Participants: 658 Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,580 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,580 records, built mostly from automated pulls of Europe PMC (62.2% of the library) and OpenAlex (17.8%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.6% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →