30,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
The number of US adults ages sixty-five and older who are living with dementia is substantial and expected to grow, raising concerns about the demands that will be placed on family members and other unpaid caregivers. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
This article reviews the significance of the Geriatric Depression Scale (GDS) to practitioners and researchers in clinical gerontology, more than 10 years after the scale was introduced to the scientific community. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Psychiatric and behavioural symptoms are frequent in nursing homes and the rate increases with the progression of the dementia. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The purpose of this study, conducted in three phases, was to develop a clinically useful observational tool (i.e., the Pain Assessment Checklist for Seniors With Limited Ability to Communicate [PACSLAC]) to assess pain in seniors with severe dementia. 1 key finding →
Design: clinical trial Evidence: low
Full summary, score breakdown and related studies → Original source
There are currently more than 38.9 million people aged 65 an older in the United States. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
A single cause of weight loss can be identified in most nursing home residents. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The Unmet Needs Model states that problem behaviors of people with dementia result from unmet needs stemming from a decreased ability to communicate those needs and to provide for oneself. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Approximately 30% (4115 dollars) of the total annual cost of AD (14420 dollars) is invested in the direct management of BPSD. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
These findings are consistent with the hypothesis that NPs are among the earliest neuropathological lesions in AD. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
BPSD are ubiquitous in nursing home residents. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
A research psychiatrist using a standardized interview found that 94% of a random sample of residents at a large, intermediate-care nursing home had mental disorders according to DSM-III criteria. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Older adults represent an ever-growing proportion of the population of the industrialised nations, with a corresponding increase in the numbers of patients with dementing disorders. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
A simple, completely objective scoring system for a clock completion test has been developed which involves only the number of digits placed in the fourth quadrant of a pre-drawn circle. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
We measured 24-hour circadian-rhythm patterns of activity and sleep/wake activity in a group of nursing-home patients (58 women and 19 men with a mean age of 85.7 years). 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
When eating difficulties arise, feeding tubes are not recommended for older adults with advanced dementia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The QoL-AD could be used as an effective measure of the quality of life of people with dementia in residential homes. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
An analysis of interaction terms in the Cox regression model found that those individuals who utilized in-home help services earlier in their dementia caregiving careers were more likely to delay institutionalization. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Life's Journey If life is indeed a journey, then poetry must be the map that reveals all its topographic possibilitiesellipsis while science is the compass that keeps us from getting lost. -R. T. Bartus, Simple Words for Complex Lives, (c) 1998 In the nearly 20 years since the cholinergic hypothesis was initially formulated, significant progress has been achieved. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Despite intensive research efforts over the past few decades, the mechanisms underlying the etiology of sporadic Alzheimer's disease (AD) remain unknown. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The ESPEN Guideline on Ethical Aspects of Artificial Nutrition and Hydration is focused on the adult patient and provides a critical summary for physicians and caregivers. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
An exponential rise in the number of older prisoners is creating new and costly challenges for the criminal justice system, state economies, and communities to which older former prisoners return. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Symptoms are common in dementia at the end of life, despite the large majority of residents receiving opioids. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The two major neurodegenerative diseases Alzheimer's disease (AD) and Parkinson's disease (PD) are characterised by low levels in the brain of the neurotransmitters acetylcholine (ACh) and dopamine (DA), respectively. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Feeding and eating difficulties leading to weight loss are common in the advanced stages of dementia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
In 2009, nearly 66 million Americans (three in 10 U.S. households) reported at least one person providing unpaid care as a family caregiver. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 30,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 30,180 records, built mostly from automated pulls of Europe PMC (64.2% of the library) and OpenAlex (16.9%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,037 records (3.4% of the library) are not peer-reviewed — 964 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →