Little is known about the relationships between infections, sepsis and dysphagia. 3 key findings →
Participants: 4,475 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Little is known about the relationships between infections, sepsis and dysphagia. 3 key findings →
Participants: 4,475 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
A large number of older persons are living in the community with undetected dementia. 5 key findings →
Participants: 252 Evidence: low
Full summary, score breakdown and related studies → Original source
3,001,987 Medicare beneficiaries were identified, of which 8.2% had a dementia diagnosis. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Older patients account for up to a quarter of all emergency department (ED) visits. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Systemic inflammation can impair cognition with relevance to dementia, delirium and post-operative cognitive dysfunction. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Study objective We sought to determine the prevalence of mental status impairment in elderly emergency department patients and to assess documentation of and referrals by emergency physicians for mental status impairment after discharge from the ED. 1 key finding →
Participants: 297 Evidence: low
Full summary, score breakdown and related studies → Original source
The diagnosis of neurosyphilis can be made with reasonable certainty if there is an appropriate neuropsychiatric syndrome associated with a positive CSF VDRL. 3 key findings →
Participants: 161 Evidence: low
Full summary, score breakdown and related studies → Original source
Neuroinflammation contributes to Alzheimer's disease (AD) progression. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Corticosteroids are widely used in modern medicine but can result in troubling psychiatric side-effects. 3 key findings →
Design: case report Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The IDEA cognitive screen performed well in these populations and should prove useful in screening for dementia and delirium in other areas of sub-Saharan Africa. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Machine learning has become ubiquitous and a key technology on mining electronic health records (EHRs) for facilitating clinical research and practice. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
HIV dementia has an annual incidence of 7% after AIDS development and eventually affects 20% of all HIV-infected persons. 4 key findings →
Participants: 34 Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Administration of hUCB-MSCs into the hippocampus and precuneus by stereotactic injection was feasible, safe, and well tolerated. 1 key finding →
Design: clinical trial Evidence: low
Full summary, score breakdown and related studies → Original source
The clbC form of methylmalonic acidaemia is a rare and poorly understood condition which results from impaired biosynthesis of methylcobalamin and adenosylcobalamin. 3 key findings →
Participants: 50 Evidence: low
Full summary, score breakdown and related studies → Original source
TPM may be useful in patients with mood disorders unresponsive to traditional therapy and warrants further clinical investigation. 1 key finding →
Participants: 58 Evidence: low
Full summary, score breakdown and related studies → Original source
In patients with Parkinson's disease (PD) disturbances of mental state constitute some of the most difficult treatment challenges of advanced disease, often limiting effective treatment of motor symptoms and leading to increased disability and poor quality of life. 1 key finding →
Evidence: high
Full summary, score breakdown and related studies → Original source
The daily rhythm in serum melatonin levels was measured in patients with dementia of the degenerate type (Alzheimer's disease, Pick's disease and senile dementia of the Alzheimer type) by radioimmunoassay. 2 key findings →
Participants: 13 Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer's disease (AD) has emerged as a key comorbidity of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
There are palliative care validated instruments to assess the sedation effect but this review shows the need for a more standardized approach when assessing it. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Pharmacological interventions for dementia include medications aimed at alleviating its core symptom: cognitive dysfunction. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia is one of the leading causes of death in the US. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The care of a patient with neurologic disease at end-of-life requires expertise in addressing advance care planning, hospice, symptom management, and caregiver support. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
In the study by Derogatis et al., which included patients with all stages of cancer, 47% of the patients met the DSM-III criteria for a psychiatric disorder, with adjustment disorders being the most common. 4 key findings →
Participants: 26 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Sixteen of 30 cases with DLB pathology had no parkinsonism, which represented diverse nigral neurodegeneration. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Of members initiated on an antimuscarinic OAB medication, 31.1% had a drug-drug or drug-disease or syndrome interaction. 5 key findings →
Participants: 66,275 Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →