27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Mild cognitive impairment (MCI) is the transitional stage between normal cognition and dementia and is associated with arterial stiffness, which may lead to cardiovascular disease. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Current evidence suggests a potential for the Mediterranean diet to prevent cognitive decline, largely supported by observational studies, although randomized controlled trials show mixed results. 1 key finding →
Evidence: high
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A 52-year-old male with early-stage Alzheimer's disease and long-standing anxiety received 30 repetitive transcranial magnetic stimulation sessions over 8 months and 20-month Mediterranean diet intervention. 5 key findings →
Evidence: low
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The results showed that the experimental group had a statistically significant difference of attention (TMT-B) and working memory scores, while the control group had no statistically significant difference for both attention and working memory. 3 key findings →
Participants: 13 Evidence: low
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To compare and rank the relative and additive effects of lifestyle components including exercise, diet, cognitive training, vascular management, and digital delivery on cognitive outcomes and dementia prevention in older adults without dementia. 1 key finding →
Evidence: low
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The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all-cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers. 2 key findings →
Evidence: low
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The StrongerMemory program, a structured intervention involving reading aloud, writing by hand, and completing simple math problems, is designed to stimulate the prefrontal cortex and enhance cognitive functioning. 5 key findings →
Evidence: low
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Family carers were food secure according to the FIES, and their overall diet quality was moderate, with a mean MEDAS score of 6.6 ± 2.1. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
This follow-up study builds on our previous research, which showed that combining strategy based cognitive training (ST) with social engagement (SE) improved memory performance in older adults more than social meetings alone. 3 key findings →
Evidence: low
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• A novel semi-immersive VR driving simulator (VRDS) for institutionalized older adults with advanced dementia. • The VRDS integrates realistic driving with a virtual environment to stimulate implicit memory and improve cognitive function. • Statistical analyses indicate improvements in game and mood scores over repeated sessions. • The system’s performance logging provides objective measures of implicit learning and motor adaptation in advanced dementia. • The logging system offers a practical alternative to standard cognitive assessments in advanced dementia. 1 key finding →
Evidence: low
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During the one-year follow-up, the intervention group showed a significant increase in mean cognitive scores (Addenbrooke's cognitive examination), rising from 73.94 to 82.32 (p < 0.001). 4 key findings →
Evidence: low
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RELEVANCE . With age, people experience a decline in cognitive and physical functions, which increases the risk of falls, loss of independence, and deterioration in quality of life. 4 key findings →
Evidence: low
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This narrative review focused on research investigating the impact of loneliness on the prevalence of dementia and its relationship with other risk factors. 2 key findings →
Design: narrative review Evidence: low
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The Ct group and Ct+ee group performed significantly better than the control group in behavioural tasks and had improved dendrite profiles of DG and basal tree of CA1 region of hippocampus. 4 key findings →
Evidence: low
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The evidence for cognitive training in preventing cognitive decline in Alzheimer's disease is varied, with some studies indicating cognitive benefits but showing limited impact on functional outcomes or disease progression. 1 key finding →
Evidence: low
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Alzheimer's Disease (AD) is a progressive neurodegenerative condition that gradually impairs cognitive abilities such as memory, attention, and problem-solving, leading to significant challenges in everyday functioning and a decline in quality of life. 1 key finding →
Evidence: low
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Evidence: low
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Cognitive training shows potential in preventing cognitive decline in individuals at risk for Alzheimer's disease, especially as part of multimodal interventions, though current evidence varies in quality and clarity. 1 key finding →
Evidence: low
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Cognitive training appears effective in improving cognitive functions and delaying cognitive decline in people at risk of Alzheimer's disease but requires more standardized research for conclusive evidence. 1 key finding →
Evidence: low
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At present, there is no cure for dementia. 5 key findings →
Evidence: low
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Eligible studies used many study designs with different sample sizes. 5 key findings →
Evidence: low
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STRUCTURED ABSTRACT INTRODUCTION This study examined the extent to which educational attainment, Alzheimer’s disease (AD) knowledge, and research attitudes are associated with willingness to participate in AD research, and whether AD knowledge and research attitudes mediate associations between educational attainment and willingness to participate. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Greater diversity of social participation was associated with better long-term cognitive maintenance among older adults with hypertension and/or diabetes. 5 key findings →
Design: longitudinal study Participants: 547 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Eight of 12 measures reached acceptable discrimination (AUC ≥ .700) for DAT vs. Semantic fluency showed the highest discrimination in each contrast, though it did not significantly outperform the NAT-S for MCI vs. In a post hoc regression, adjusting for cognitive flexibility and working memory attenuated group differences; the DAT difference was no longer significant, whereas the MCI difference remained significant. 3 key findings →
Participants: 286 Evidence: low
Full summary, score breakdown and related studies → Original source
Recruitment (88.0%) and protocol fidelity (100%) met or exceeded prespecified progression criteria, whereas retention and follow-up data availability were 59.1% (13/22), slightly below the predefined 60% criterion. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →