27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
This will be vital in moving to a phase III trial that is pragmatic and feasible for these complex patients within the NHS. 2 key findings →
Design: randomized controlled trial Participants: 40 Evidence: high
Full summary, score breakdown and related studies → Original source
Hospice enrollment results in lower combined Medicare/Medicaid expenditures in the last month of life, particularly among short-stay NH residents. 3 key findings →
Design: cohort study Participants: 5,774 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Using 12-year longitudinal data from deceased participants of the Berlin Aging Study (N = 414; age 70-103 years, at first occasion; M = 87 years, SD = 8.13), the authors examined whether and how old and very old individuals exhibit terminal decline in reported life satisfaction at the end of life. 2 key findings →
Design: longitudinal study Participants: 414 Evidence: moderate
Full summary, score breakdown and related studies → Original source
To evaluate the impact hospice enrollment has on the terminal care of patients with dementia and describe the symptom burden these patients experience, caregivers of dementia decedents were assessed in a mortality follow-back survey. 5 key findings →
Participants: 135 Evidence: low
Full summary, score breakdown and related studies → Original source
This review reinforces the importance of providing appropriate palliative care to individuals suffering from end-stage dementia and identifies some of the barriers to extending such specialist palliative care provision. 3 key findings →
Participants: 100,000 Evidence: low
Full summary, score breakdown and related studies → Original source
Educational level was an independent predictor of end-of-life preferences after hearing a verbal description of advanced dementia. 5 key findings →
Participants: 104 Evidence: low
Full summary, score breakdown and related studies → Original source
Based on these preliminary findings, consensus criteria for prescribing in advanced dementia are needed to decrease polypharmacy and reduce the use of medications that are of minimal benefit or high risk. 2 key findings →
Participants: 34 Evidence: low
Full summary, score breakdown and related studies → Original source
Persons with advanced dementia are frequently exposed to antimicrobials, especially during the 2 weeks before death. 2 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
Alzheimer's disease, AD, is the most common form of dementia. 5 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
Neuropsychiatric symptoms (NPS) are common in dementia, although little is known about their prevalence and treatment near the end of life. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The aim of the present study was to clarify the processes of decision making and end-of-life care for patients with dementia in the group homes in Japan. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
When caring for people with severe Alzheimer's disease (AD), the concept of the person being central is increasingly advocated in clinical practice and academia as an approach to deliver high-quality care. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Some indicators imply a less than optimal quality of care (restraints, pressure sores, psychoactive drugs, and the lack of documentation of shared decision-making) and suggest that far advanced demented patients are not fully perceived as "terminal." 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Although not significant, results as to the effectiveness of such an intervention to improve family satisfaction with end-of-life care are encouraging. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
For advance directives to better reflect a person's wishes, discussions with individuals and families about advance directives should include a range of care issues in the settings of terminal illness, persistent vegetative state or end-stage illness. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Our results indicated that patient diagnosis (cancer or dementia) and caregiver appraisals (stressfulness of functional impairment and positive aspects of caregiving) were not predictors on any of our well-being outcomes. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
We noted no differences between decedents with and without dementia in terms of pain, psychosocial status, family involvement, advance care planning, most life-prolonging interventions, and hospice use. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The single most common cause of death occurring within the nursing home was Alzheimer's, with most dying appropriately on hospice care. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →