A total of 2056 papers related to machine learning in patients with MCI were retrieved from the Wo SCC database. 5 key findings →
Participants: 2,056 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Research
27,780 Alzheimer's and dementia studies in plain English, each scored out of 100.
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder that involves dysregulation of many cellular and molecular processes. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The extracellular matrix (ECM) is a critical regulator of neural network development and plasticity. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Accurately identifying the patients that have mild cognitive impairment (MCI) who will go on to develop Alzheimer's disease (AD) will become essential as new treatments will require identification of AD patients at earlier stages in the disease process. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Studies of patients with semantic impairments following brain damage offer key insights into the cognitive and neural organization of semantic memory. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
In recent years, there has been a great interest in computer-aided diagnosis of Alzheimer's Disease (AD) and its prodromal stage, Mild Cognitive Impairment (MCI). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
A new chaos-wavelet approach is presented for electroencephalogram (EEG)-based diagnosis of Alzheimer's disease (AD) employing a recently developed concept in graph theory, visibility graph (VG). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Traditionally, lymphocytic interferon γ (IFN-γ) was considered to be a simple 'booster' of proinflammatory responses by microglia (brain-resident macrophages) during bacterial or viral infection. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that has been increasingly used to image the retinal vasculature at capillary level resolution. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Patients with frontotemporal dementia have pervasive changes in emotion recognition and social cognition, yet the neural changes underlying these emotion processing deficits remain unclear. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Machine learning algorithms and multivariate data analysis methods have been widely utilized in the field of Alzheimer's disease (AD) research in recent years. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
With the rapid generation of spatial transcriptomics (ST) data, integrative analysis of multiple ST datasets from different conditions, technologies and developmental stages is becoming increasingly important. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Spatial molecular profiling of complex tissues is essential to investigate cellular function in physiological and pathological states. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The QICDSS provides a way of producing population-based data on the chronic disease burden, health services and prescription drug uses. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The objective of this study was to determine the accuracy of administrative data (by use of hospital discharge codes) for measuring comorbidity in patients with heart disease. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Reasonable prognostic information for 1-year mortality in older patients discharged from general medicine services can be derived from administrative data to identify high-risk groups of persons. 2 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
Cost estimates did not differ significantly between CN and MCI. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Although the warnings slowed the growth in the use of atypical antipsychotic drugs among patients with dementia, they did not reduce the overall prescription rate of these potentially dangerous drugs. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Recent studies have been cautiously optimistic about declining trends in dementia prevalence and incidence. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia poses a substantial additional burden to the German social security system, with the long-term care sector being more seriously challenged than the health care sector. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Diabetic patients have an elevated risk of dementia, and comorbidity increases this risk. 1 key finding →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
This study provides evidence that the increase in dementia-free life years went together with an absolute compression of life years with dementia. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Only about one-third of individuals with COPD in Ontario, Canada, received PFT to confirm their diagnosis; age, comorbidity, and physician factors appear to influence its use. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
High-frequency stimulation of the subthalamic nucleus (STN) constitutes one of the most effective treatments for advanced forms of Parkinson's disease. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Patients with mild to moderate Parkinson disease showed impaired visual perception and cognition compared with elderly control subjects. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Where “Free full text” comes from
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
How the 0–100 score works — and why some entries are capped
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
- Journal tier up to 10 pts
- Journal's citation record up to 4 pts
- Study design up to 12 pts
- Strength of evidence up to 5 pts
- Peer-review validation up to 10 pts
- How recent up to 5 pts
- Sample size up to 4 pts
- Effect reported up to 3 pts
- Studied in people up to 3 pts
- Randomised / blinded up to 2 pts
- Times cited up to 7 pts
- Citations per year up to 5 pts
- Impact for its field and year up to 6 pts
- Cited by studies here up to 6 pts
- Still being cited up to 4 pts
- Senior author's track record up to 4 pts
- Institution's track record up to 3 pts
- Multi-centre collaboration up to 3 pts
- Indexed in PubMed up to 2 pts
- Free to read up to 2 pts
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,780 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
What this library is — and isn't
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,780 records, built mostly from automated pulls of Europe PMC (61.1% of the library) and OpenAlex (18.3%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →