The mean age of the CI subjects was 83, and 83% were women. 3 key findings →
Participants: 104 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Research
27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
A reasonably accurate, validated model has been produced, with clinical application through a scored point system, to assist clinicians, residents, and family members in defining good goals of care around end-of-life care. 1 key finding →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
These results suggest that management of patients with advanced DAT on a DSCU using a palliative care philosophy may result in less patient discomfort and lower costs than management on a TLTC. 2 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Irrespective of antibiotic treatment, pneumonia causes substantial suffering in demented patients. 2 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Underlying cause of death has a marked effect on place of death. 3 key findings →
Participants: 125,242 Evidence: low
Full summary, score breakdown and related studies → Original source
Most very old community-dwelling individuals, especially the severely cognitively impaired, died away from home. 4 key findings →
Design: prospective cohort Evidence: moderate
Full summary, score breakdown and related studies → Original source
The paper highlights elevated levels of burden experienced by patients with palliative care requirements. 4 key findings →
Participants: 185 Evidence: low
Full summary, score breakdown and related studies → Original source
Further investments to facilitate dying at home are desirable. 2 key findings →
Participants: 135,000 Evidence: low
Full summary, score breakdown and related studies → Original source
The ZBI-7 is a valid instrument for measuring caregiver burden in PC. 2 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Further guidelines should be developed to help clinicians to promptly refer terminal cancer and non-cancer patients to hospice care. 5 key findings →
Participants: 8,459 Evidence: low
Full summary, score breakdown and related studies → Original source
52/100
Hospital-based palliative care is primarily utilized to clarify goals of care in neurological patients and that advance directives were commonly not completed prior to consultation. 2 key findings →
Participants: 3,170 Evidence: low
Full summary, score breakdown and related studies → Original source
Overall, patients dying as a result of non-cancer diseases were twice as likely to be admitted to ICUs at the EOL as patients dying due to cancer. 5 key findings →
Participants: 240,757 Evidence: low
Full summary, score breakdown and related studies → Original source
The potential adverse effects of prophylactic bilateral oophorectomy on heart health, neurological health, bone health and quality of life should be carefully weighed against its potential benefits for cancer risk reduction in women at average risk of ovarian cancer. 3 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Most patients who enter hospice care do so late in the course of their terminal illnesses. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Executive dysfunction was found to be associated with relapse and recurrence of geriatric major depression and with residual depressive symptoms. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
By 2050, the American 85 years old and over population will triple. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
A video of a patient with advanced dementia may overcome communication barriers associated with low health literacy. 4 key findings →
Participants: 80 Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Geriatric depression is prevalent in rural south India. 5 key findings →
Participants: 1,000 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
51/100
During the study period, the risk of mortality in hip fracture patients was 3-fold higher than that in the general population and included every major cause of death. 2 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Approximately 7 of 10 SICU and TICU patients experience delirium. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The aim of this study is to establish the existing relationship among variables referred to the person, specifically age and gender, and the functional dependence in basic ADL and in IADL, as well as the possible relationship it has with the increase of morbidity and mortality in a random sample of 598 individuals older than 65 years. 1 key finding →
Participants: 598 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Most inpatient users of VR described the experience as pleasant and capable of reducing pain and anxiety. 4 key findings →
Participants: 510 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
This study confirms that healthy senior citizens as well as senior citizens with underlying medical conditions are at risk for the serious complications of influenza and benefit from vaccination. 2 key findings →
Participants: 20,000 Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Patients with CLTI undergoing peripheral vascular intervention from 2017 to 2018 were derived from the Medicare-linked VQI (Vascular Quality Initiative) registry. 5 key findings →
Participants: 114 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
51/100
We identified all participants in the UK Biobank cohort study diagnosed with HF prior to enrolment or during follow-up, who had disease occurrence data available from both primary and secondary care records (n = 9824). 5 key findings →
Design: cohort study Participants: 9,824 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
From across this tag
10 of the 862 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Disability in geriatric depression
- Association of 3-Year Multidomain Intervention and Omega-3 Supplementation with Frailty Incidence
- Occurrence, associated factors, and outcomes of delirium in patients in an adult acute general medicine service in England: a 10-year longitudinal, observational study
- Evaluation of Racial Disparities in Hospice Use and End-of-Life Treatment Intensity in the REGARDS Cohort
- Hypnotics should not be considered for the initial treatment of chronic insomnia. Con
- Presenting complaints and emergency triage priority of older adults hospitalized with delirium: a retrospective cohort study
- Interventions for improving palliative care for older people living in nursing care homes
- Attitudes Toward Advance Directives Among Patients and Their Family Members in China
- Depressive disorders in primary care: prevalence, functional disability, and identification
- Burden of Cause-Specific Mortality Associated With PM2.5 Air Pollution in the United States
Where “Free full text” comes from
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
How the 0–100 score works — and why some entries are capped
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
- Journal tier up to 10 pts
- Journal's citation record up to 4 pts
- Study design up to 12 pts
- Strength of evidence up to 5 pts
- Peer-review validation up to 10 pts
- How recent up to 5 pts
- Sample size up to 4 pts
- Effect reported up to 3 pts
- Studied in people up to 3 pts
- Randomised / blinded up to 2 pts
- Times cited up to 7 pts
- Citations per year up to 5 pts
- Impact for its field and year up to 6 pts
- Cited by studies here up to 6 pts
- Still being cited up to 4 pts
- Senior author's track record up to 4 pts
- Institution's track record up to 3 pts
- Multi-centre collaboration up to 3 pts
- Indexed in PubMed up to 2 pts
- Free to read up to 2 pts
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
What this library is — and isn't
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →