27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Where appropriate, we undertook subgroup analysis by modality (individual versus group), number of sessions and frequency, setting (community versus care home), type of control condition and dementia severity. 5 key findings →
Design: systematic review Participants: 37 Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
There was some evidence that the use of smartphones and tablets could aid cognitive function in older adults without cognitive impairment, particularly executive function and processing speed. 1 key finding →
Design: systematic review Participants: 28 Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
MYB will be the largest internet-based trial to attempt to prevent cognitive decline and potentially dementia. 5 key findings →
Design: randomized controlled trial Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Older adults with cognitive disorders can learn smartphone-based memory strategies and doing so benefits prospective memory functioning and independence. 2 key findings →
Design: randomized controlled trial Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Hearing impairment in older adults is independently associated in longitudinal studies with accelerated cognitive decline and incident dementia, and in cross-sectional studies, with reduced volumes in the auditory cortex. 5 key findings →
Design: cross-sectional Participants: 126 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
PARO may have some effect on motor activity of older people with dementia in long-term care, but not on sleep patterns. 2 key findings →
Design: randomized controlled trial Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
An individual's brainAGE is the difference between chronological age and age predicted from machine-learning models of brain-imaging data. 2 key findings →
Design: cross-sectional Participants: 869 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Digital literacy may help reduce cognitive decline among persons aged between 50 and 89 years. 2 key findings →
Design: longitudinal study Participants: 6,442 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Both interventions were highly feasible and acceptable and allowed improvement in different aspects of cognitive and psychosocial functioning in MCI subjects. 4 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
MCI is highly prevalent in older adults with profound hearing loss. 3 key findings →
Design: longitudinal study Participants: 70 Evidence: moderate
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We aimed to characterise the brain structure of superagers and identify demographic, lifestyle, and clinical factors associated with this phenotype. 4 key findings →
Design: longitudinal study Participants: 64 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Electroacupuncture was an effective treatment for MCI patients by improving cognitive function. 4 key findings →
Design: meta-analysis Participants: 103 Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
There are variations in the interventions, such as location and dosage. 5 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
In older adults, hearing loss is independently associated with an increased rate of cognitive decline, and has been identified to be a modifiable risk factor for dementia. 5 key findings →
Design: longitudinal study Participants: 59 Evidence: moderate
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Based on the systematic review, evidence suggests that treating hearing loss in persons with cognitive impairment can have benefits to communication and quality of life. 4 key findings →
Design: randomized controlled trial Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
The results demonstrated that CCIs have beneficial effects on domain-specific cognition in people with MCI but no significant effects on people with dementia. 5 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Adjusted for demographic and health behavior as well as health condition risk factors, desktop and cellphone ownership were independently associated with subsequent decreased cognitive decline over the four-year period. 2 key findings →
Design: longitudinal study Evidence: moderate
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Higher levels of physical activity are known to benefit aspects of brain health across the lifespan. 5 key findings →
Evidence: low
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TBI patients' brains were estimated to be older than their chronological age. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Even without subjective cognitive complaints, higher risk of cognitive impairment is presented in the prefrail and frail individuals. 5 key findings →
Design: cross-sectional Participants: 1,686 Evidence: moderate
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Causal pathways corresponding to all 4 hypotheses were supported. 2 key findings →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Hearing loss is a modifiable risk factor for dementia in older adults. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Dual-task gait and other detailed gait metrics provide value for identifying CF above gait speed alone. 1 key finding →
Participants: 41 Evidence: low
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These findings reinforce the usability of speech as a reliable biomarker in the detection and assessment of apathy. 3 key findings →
Participants: 60 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
It is a piece of evidence that cognitive dysfunction, even in early stage of memory decline, may have some bad impact on balance and gait regardless of the effect of musculoskeletal problems. 5 key findings →
Design: post-hoc analysis Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →