27,780 Alzheimer's and dementia studies in plain English, each scored out of 100.
The study findings demonstrate high user satisfaction with telehealth in a rural memory clinic and the sound psychometric properties of the TeSS in this population. 2 key findings →
Participants: 223 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
A study of item bias in standard cognitive screening measures was conducted in a sample of Afro-American, Hispanic and non-Hispanic white elderly respondents who were part of a dementia case registry study. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Global efforts to improve the health of women largely focus on improving sexual and reproductive health. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Hispanic subjects were, on average, significantly younger and had less years of education than African Americans or whites. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
The findings suggest that specific cultural attitudes towards the caregiving role have important implications for how carers can best be supported. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Alzheimer's disease (AD) is the most common cause of dementia in the elderly and the sixth leading cause of death in the United States. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Increasing age (especially >60 years) may be the most important risk factor for severe outcomes. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Accurate assessment of cognitive impairment requires comparison of cognitive performance in individuals to performance in a comparable healthy normative population. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
We describe the largest series of patients with TARDBP mutations presenting with frontotemporal dementia (FTD) and review the cases in the literature to precisely characterize FTD diseases associated with this genotype. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Hypertension is a highly prevalent condition with numerous health risks, and the incidence of hypertension is greatest among older adults. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Communication for people with dementia and with people with dementia for all persons involved in care (including family members, medical staff and therapists, and members of the community) can be very challenging. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Through various manifestations, social inappropriateness is frequently the first clinical sign of a neurodegenerative process, especially in AD and bvFTD, years before noticeable impairment on classical neuropsychological assessment and brain atrophy on imaging. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The number of elderly is growing rapidly, including those that struggle with cognitive decline and, consequently, activities of daily living. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Machine learning has become ubiquitous and a key technology on mining electronic health records (EHRs) for facilitating clinical research and practice. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are considered to be part of a spectrum. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The non-fluent/agrammatic variant of primary progressive aphasia (nfvPPA) and the behavioral variant frontotemporal dementia (bvFTD) are focal neurodegenerative disorders belonging to the FTD-spectrum clinical syndromes. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The white matter FC decreased in late MCI and AD dementia patients compared to CN participants, and this decrease was correlated with cognitive measures. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Alzheimer disease (AD) is a neurodegenerative disorder characterized pathologically by the presence of neurofibrillary tangles and amyloid beta (Aβ) plaques in the brain. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Longer age-related decision making latencies may reflect a greater need for working memory and increased self-monitoring in older subjects. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The Cache County Study of Memory in Aging (CCMS) is an epidemiological study of Alzheimer's disease (AD), mild cognitive disorders, and aging in a population of exceptionally long-lived individuals (7th to 11th decade). 1 key finding →
Participants: 507 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The results suggest that it is possible to automatically quantify the task quality of smart home activities and perform limited assessment of the cognitive health of individual if smart home activities are properly chosen and learning algorithms are appropriately trained. 3 key findings →
Participants: 263 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
One in 8 patients presented with moderate speech timing deficits with a further two-thirds rated as mild or subclinical. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Machine learning models are promising alternatives for estimating the genetic risk of LOAD. 3 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
The clinical symptoms of dementia include difficulty with speech, poor short-term memory, and changes in behavior. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The repeated head trauma experienced by boxers can lead to the development of dementia pugilistica (DP)--punch drunk syndrome. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled.
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,780 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,780 records, built mostly from automated pulls of Europe PMC (61.1% of the library) and OpenAlex (18.3%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →