27,780 Alzheimer's and dementia studies in plain English, each scored out of 100.
Alzheimer's disease (AD) is the most prevalent dementia, but it shows similar initial symptoms to other neurocognitive diseases (Lewy body disease (LBD) and frontotemporal dementia (FTD)). 1 key finding →
Participants: 50 Evidence: low
Full summary, score breakdown and related studies → Original source
Pairwise comparisons among the three groups showed that compared with the health checkup (HC) group, serum NfL and GFAP were increased in both AD and MCI (PNfL < 0.05, PGFAP < 0.01). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Among diagnostic groups, highest plasma Nfl and t-tau concentrations were detected in CJD (fold changes of 38 and 18, respectively, compared to HC). 5 key findings →
Participants: 70 Evidence: low
Full summary, score breakdown and related studies → Original source
Pre-analytical immunoprecipitation resulted in a significant increase in the area under the ROC curve (AUC) from 0.73 to 0.88 (p = 0.01547) for identifying subjects with abnormal CSF Aβ42/40. 4 key findings →
Participants: 42 Evidence: low
Full summary, score breakdown and related studies → Original source
The proteomic profile discriminated DLB and PD from NC with an AUC (Area Under the Curve) of 0.96 with demographics of age, sex and education. 4 key findings →
Participants: 89 Evidence: low
Full summary, score breakdown and related studies → Original source
The novel IP-MS assay measuring the Aβ42/40 ratio demonstrated an AUC of 0.82 for differentiating AD from control subjects. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
There were significant positive correlations between the predicted MMSE scores and ground truth scores in the Patient and Healthy groups (r = 0.66, p < 0.001). 5 key findings →
Participants: 202 Evidence: low
Full summary, score breakdown and related studies → Original source
Computerized cognitive assessment tools may facilitate early identification of dementia in the primary care setting. 1 key finding →
Participants: 259 Evidence: low
Full summary, score breakdown and related studies → Original source
By incorporating sex, place of residence, age, and years of education as covariates, the TabCAT-BHA demonstrated greater accuracy in detecting cognitive impairment (AUC = 75.3%) compared to the MMSE (AUC = 66.4%) and RUDAS (AUC = 71.4%). 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Recently, transfer learning has been successfully applied in early diagnosis of Alzheimer's Disease (AD) based on multi-domain data. 1 key finding →
Participants: 807 Evidence: low
Full summary, score breakdown and related studies → Original source
Average adherence was 41%. Despite this, remote measures demonstrated excellent reliability (ICCs > 0.90 after 10 sessions) and strong construct validity, with tasks loading onto memory, attention, and executive function domains. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
Why assessment is of practical consequence to anaesthetistsGeneral Health Questionnaire (GHQ) in general hospitals: selecting a set of items using a stepwise hierarchical procedurePain assessment in cognitively impaired and unimpaired older adults: a comparison of four scalesMental disorders among internal medical inpatientsSuicide in Later Life: A Review and Recommendations for PreventionDELIRIUM IN THE TERMINALLY ILLRecognition of psychiatric disorders in nonpsychiatric hospital wardsNursing documentation versus standardized assessment of cognitive status in hospitalized medical patientsCompleted Suicide Among Older Patients in Primary Care Practices: A Controlled StudyDoes myasthenia gravis affect the brain?SUICIDAL PATIENTS IN THE ED: ETHICAL ISSUESMethodological issues of an epidemiological study: From the results of a study on psychological problems seen in outpatients visiting the internal medicine departments of general hospitalsPsychiatric disorders and vertigoTotal Quality Management and Geriatric CareAssessment and treatment of depression in the cancer patientUse of hospital services by AIDS patients with psychiatric illnessNeuropsychological and Pharmacokinetic Assessment of Hospice Inpatients Receiving MorphineMANAGEMENT OF SUICIDAL BEHAVIOR IN THE ELDERLYLiteraturverzeichnisSuicide in later lifeMajor depression in the primary care settingMaking the diagnosis of depression in the primary care settingThe Mini-Mental State Examination in General Medical Practice: Clinical Utility and AcceptancePsychological Morbidity in Obstetric-Gynaecology Patients: Testing the Need for Expanded Psychiatry Services in Obstetric-Gynaecology FacilitiesPrevalence of Psychiatric Disorders in Medical InpatientsTranstornos do humor em enfermaria de clínica médica e validação de escala de medida (HAD) de ansiedade e depressãoDelirium in Elderly Patients: Evaluation and ManagementDelirium Presenting With Symptoms of DepressionAnalysis of the terms used by general practitioners to characterize patients considered by them as depressed.
Participants: 100 Evidence: low
Full summary, score breakdown and related studies → Original source
The National Institute on Aging and the Alzheimer's Association convened three separate work groups in 2011 and single work groups in 2012 and 2018 to create recommendations for the diagnosis and characterization of Alzheimer's disease (AD). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
We investigated whether the cerebrospinal fluid (CSF) biomarkers beta-amyloid 1-42 (Abeta1-42), total tau (t-tau) protein and tau protein phosphorylated at threonine 181 (p-tau181) could discriminate Alzheimer's disease (AD) from vascular dementia (VD) patients. 4 key findings →
Participants: 35 Evidence: low
Full summary, score breakdown and related studies → Original source
Our findings provide evidence that greater concentrations of KP metabolites are associated longitudinally over two years with greater biomarker evidence of neurofibrillary tau pathology (pTau-181), neuroinflammation (GFAP), and neurodegeneration (NfL), suggesting that dysregulated KP metabolism may play a role in ADRD pathogenesis. 4 key findings →
Participants: 301 Evidence: low
Full summary, score breakdown and related studies → Original source
Our study revealed the possibility of urinary formic acid as a potential novel biomarker for the early diagnosis of AD. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
FDG-PET and amyloid PET imaging are valuable in the assessment of patients with Alzheimer's disease. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Alzheimer's disease is the leading cause of dementia. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
In recent years, patients who are at high risk for developing Alzheimer's disease (AD) have become a focus of study. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Debate exists regarding differences in the prevalence of Alzheimer disease (AD) in African Americans and Hispanics in the United States, with some evidence suggesting that the prevalence of AD may be considerably higher in these groups than in non-Hispanic whites. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The merit of screening for dementia and cognitive impairment has been the subject of recent debate. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Alzheimer disease is the most common cause of dementia and the fifth leading cause of death in adults older than 65 years. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
We describe the full history and postmortem findings in one of the first identified cases of mitochondrial encephalomyopathy with stroke-like episodes (MELAS). 5 key findings →
Participants: 69 Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
The objectives of this study were to assess whether Teng's modification of the Mini-Mental State Examination (MMSE) improves its performance as a screening test for cognitive impairment and dementia, and to replicate this comparison in French and English language groups, and for differing assumptions concerning the relative importance of false negative and false positive errors. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Previous studies have indicated a prevalence of dementia in older admissions of ∼42% in a single London teaching hospital, and 21% in four Queensland hospitals. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
10 of the 1,775 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,780 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,780 records, built mostly from automated pulls of Europe PMC (61.1% of the library) and OpenAlex (18.3%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →