Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 176–200 of 7,816 matching trials · page 8 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
A Multimodal Music Therapy Intervention for Engaging Persons With Severe Dementia
NCT06605157
AMUSED; Reading Aloud
Runs in: United States · 8 sites
NA
other
ACTIVE_NOT_RECRUITING 45 Alaine E Hernandez, PhD
OTHER
2026-09-04
Olfactory Training in Mild Cognitive Impairment
NCT06825403
Olfactory Memory Training; Visual Memory Training
Runs in: United States · 1 site
NA
other
RECRUITING 30 Jeffrey Motter
OTHER
2026-09-04
Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers
NCT06940687
Pre-recorded Music Session; Live Music Session
Runs in: United States · 2 sites
NA
other
ACTIVE_NOT_RECRUITING 60 Yale University
OTHER
2026-09-04
Remotely-supervised Neuromodulation in PPA
NCT07260253
Lexical Retrieval Cascade Treatment; Remotely Supervised Transcrani...
Runs in: United States · 2 sites
NA
other
RECRUITING 80 Maya Henry
OTHER
2026-09-04
A First-in-human Study of the Effects of SRP-1005 in Participants With Huntington's Disease
NCT07536061
SRP-1005; Placebo
Runs in: Australia; New Zealand; Switzerland; United Kingdom · 4 sites
PHASE1
other
RECRUITING 32 Sarepta Therapeutics, Inc.
INDUSTRY
2026-09-04
A Study of LY3439539 in Participants With Alzheimer's Disease
NCT07598370
LY3439539
Runs in: Australia; New Zealand; Singapore; United States · 11 sites
PHASE1
other
RECRUITING 30 Eli Lilly and Company
INDUSTRY
2026-09-04
A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)
NCT07636811
Mivelsiran; Placebo
Runs in: Spain; United States · 3 sites
PHASE2
other
RECRUITING 58 Alnylam Pharmaceuticals
INDUSTRY
2026-09-04
An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease
NCT07764146
VY1706 Low dose; VY1706 Mid dose; VY1706 High Dose; Anti-AAV9 Total...
Runs in: United States · 1 site
PHASE1
gene-therapy
RECRUITING 18 Voyager Therapeutics
INDUSTRY
2026-09-04
A Study of MK-2214 in Adults With Mild Cognitive Impairment or Mild-to-Moderate Alzheimer's Disease (MK-2214-002)
NCT05466422
MK-2214; Placebo
Runs in: United States · 12 sites
PHASE1
other
COMPLETED 34 Merck Sharp & Dohme LLC
INDUSTRY
2026-09-03
Florida Cerebrovascular Disease Biorepository and Genomics Center
NCT05491980
Runs in: United States · 1 site
NA
other
ACTIVE_NOT_RECRUITING 72 Mayo Clinic
OTHER
2026-09-03
RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies
NCT05869669
Neflamapimod; Placebo
Runs in: Netherlands; United Kingdom; United States · 40 sites
PHASE2
other
COMPLETED 159 EIP Pharma Inc
INDUSTRY
2026-09-03
ADRC Clinical Cohort (Alzheimer's Disease)
NCT06703541
Runs in: United States · 1 site
NA
other
RECRUITING 500 Duke University
OTHER
2026-09-03
Comfortage - AD Prevention Strategies
NCT06896201
Neuropsychological Assessments and Other Questionnaires; Blood Exam...
Runs in: Italy · 1 site
NA
other
ACTIVE_NOT_RECRUITING 200 Fondazione Policlinico Universitario Agostino Gemelli IRCCS
OTHER
2026-09-03
Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial
NCT07377981
Esketamine combined with dexmedetomidine; Dexmedetomidine
Runs in: China · 1 site
PHASE4
other
NOT_YET_RECRUITING 356 The First Affiliated Hospital with Nanjing Medical University
OTHER
2026-09-03
Efavirenz for the Treatment of Creutzfeldt-Jakob Disease
NCT07482085
Efavirenz; Placebo
Runs in: China · 1 site
PHASE3
other
RECRUITING 246 Xuanwu Hospital, Beijing
OTHER
2026-09-03
Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation
NCT07624448
Regulating Together group therapy
Runs in: United States · 1 site
NA
other
RECRUITING 10 Children's Mercy Hospital Kansas City
OTHER
2026-09-03
Longitudinal Profiling of Plasma-Derived Glial Extracellular Vesicles in Alzheimer's Disease
NCT07803055
blood sampling
Runs in: Italy · 1 site
NA
other
RECRUITING 48 Fondazione Policlinico Universitario Agostino Gemelli IRCCS
OTHER
2026-09-03
Life's End Benefits of cannaBidiol and tetrahYdrocannabinol
NCT05644262
T2:C100; Placebo
Runs in: United States · 10 sites
PHASE2
other
COMPLETED 120 University of Southern California
OTHER
2026-09-02
Adaptation of the Uniform Data Set for Telematic Administration
NCT05785910
IUDS
Runs in: Italy · 1 site
NA
other
COMPLETED 14 Fondazione Policlinico Universitario Agostino Gemelli IRCCS
OTHER
2026-09-02
Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline
NCT05907343
Closed-loop TBS; Open-loop TBS
Runs in: United States · 1 site
NA
other
RECRUITING 180 University of Texas at Austin
OTHER
2026-09-02
Supporting Our Caregivers In ADRD Learning (SOCIAL)
NCT06276023
Mindful and Self-Compassionate Care Program (MASC); Health Educatio...
Runs in: United States · 1 site
NA
other
COMPLETED 82 Massachusetts General Hospital
OTHER
2026-09-02
Autonomic Involvement in Patient With Cognitive Decline
NCT06292741
Sudoscan
Runs in: Italy · 1 site
NA
other
RECRUITING 120 Fondazione Policlinico Universitario Agostino Gemelli IRCCS
OTHER
2026-09-02
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
NCT06596746
Observation
Runs in: Italy · 1 site
NA
other
RECRUITING 600 Casa di Cura San Raffaele Cassino
NETWORK
2026-09-02
A Study of Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease
NCT06996730
Donanemab; RG6289; Donanemab placebo; RG6289 placebo
Runs in: Colombia · 1 site
PHASE2|PHASE3
anti-amyloid-antibody
RECRUITING 240 Banner Health
OTHER
2026-09-02
Mazdutide in Type 2 Diabetes With Early-Stage Cognitive Impairment (LIGHT-COG Study)
NCT07083154
Mazdutide; Placebo
Runs in: China · 8 sites
PHASE3
other
RECRUITING 420 The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
OTHER
2026-09-02

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →