Find an Alzheimer's clinical trial

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

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"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 76–100 of 7,816 matching trials · page 4 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial	Phase	Status	Enrolled	Sponsor	Last updated
A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease NCT06585449 ALN-HTT02; Placebo Runs in: Canada; Germany; United Kingdom · 19 sites	PHASE1 other	RECRUITING	66	Alnylam Pharmaceuticals INDUSTRY	2026-09-16
A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE) NCT06682767 FMD1 (LNT22-017-1); Rapamycin; Placebo Runs in: United States · 1 site	PHASE1\|PHASE2 other	NOT_YET_RECRUITING	60	Cedars-Sinai Medical Center OTHER	2026-09-16
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3) NCT06937229 KarXT; KarX-EC Runs in: Argentina; Brazil; Bulgaria; Canada; Chile; China; Croati... · 252 sites	PHASE3 other	RECRUITING	650	Bristol-Myers Squibb INDUSTRY	2026-09-16
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1) NCT07011732 Xanomeline/Trospium Chloride Capsule; Xanomeline Enteric Capsule; Placebo Runs in: Argentina; Brazil; Bulgaria; Canada; China; Croatia; Gree... · 162 sites	PHASE3 other	RECRUITING	426	Bristol-Myers Squibb INDUSTRY	2026-09-16
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease NCT07011745 Xanomeline/Trospium Chloride Capsule; Xanomeline Enteric Capsule; Placebo Runs in: Argentina; Chile; Czechia; France; Germany; Hungary; Isra... · 144 sites	PHASE3 other	RECRUITING	426	Bristol-Myers Squibb INDUSTRY	2026-09-16
Multi-session Transcranial Alternating Current Stimulation to Improve Dual-task Standing and Brain Activity in Older Adults With Mild Cognitive Impairment NCT07097051 real tACS; sham tACS Runs in: United States · 1 site	PHASE2 other	ACTIVE_NOT_RECRUITING	20	High Point University OTHER	2026-09-16
InRAD Observational Study NCT07213700 None, this is a non-interventional observational study Runs in: Australia; Austria; Belgium; Brazil; Czechia; Greece; Ire... · 18 sites	NA other	RECRUITING	50,000	Stichting International Registry for Alzheimer's Disease and other Dementias Foundation OTHER	2026-09-16
Cooking Health-Oriented Meals to Prevent Dementia and Diabetes NCT07661368 Cooking skills training including in-person classes; Cooking skills... Runs in: United States · 1 site	NA other	RECRUITING	40	Virginia Polytechnic Institute and State University OTHER	2026-09-16
Personalized Brain Health Service and Dementia Prevention NCT07698431 Multimodal Lifestyle Intervention; Lifestyle Recommendations and Counseling Runs in: Spain · 1 site	NA other	RECRUITING	120	Barcelonabeta Brain Research Center, Pasqual Maragall Foundation OTHER	2026-09-16
A Postmarketing Study of Lecanemab for the Treatment of Participants With Alzheimer's Disease NCT07821658 No Intervention Runs in: United States · 1 site	NA anti-amyloid-antibody	RECRUITING	6,700	Eisai Inc. INDUSTRY	2026-09-16
Effects of an Exercise Snacking Intervention on Cognitive Function in Patients With Mild Cognitive Impairment: A Nationwide Multicenter Randomized Controlled Trial NCT07822867 Baduanjin-Based Exercise Snacking	NA other	NOT_YET_RECRUITING	240	Peking University OTHER	2026-09-16
Development and Preliminary Application Evaluation of a Clinical Decision Support Training Platform for Dementia Care NCT07823634 care decision support training platform program	NA other	NOT_YET_RECRUITING	130	Chang Gung Memorial Hospital OTHER	2026-09-16
Natural History Study of CADASIL NCT05072483 MRI Runs in: United States · 1 site	NA other	RECRUITING	155	National Heart, Lung, and Blood Institute (NHLBI) NIH	2026-09-15
Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type NCT05397639 Masupirdine 50 mg; Masupirdine 100 mg; Placebo Runs in: Croatia; Poland; Serbia; United States · 44 sites	PHASE3 other	ACTIVE_NOT_RECRUITING	375	Suven Life Sciences Limited INDUSTRY	2026-09-15
Making Connections Thru Music NCT06079216 Volunteer Led Making Connections Thru Music; Staff Led Making Conne... Runs in: United States · 2 sites	NA other	RECRUITING	196	Hopeful Aging INDUSTRY	2026-09-15
The BRAIN App (Phase 2 SBIR) NCT06298474 The BRAIN App Runs in: United States · 1 site	NA other	RECRUITING	120	Hopeful Aging INDUSTRY	2026-09-15
TDCS as Augmentation Therapy to Cognitive Training in Mild Dementia NCT06559254 transcranial direct current stimulation Runs in: Hong Kong · 1 site	NA other	COMPLETED	36	Hospital Authority, Hong Kong OTHER_GOV	2026-09-15
Phase I Clinical Study of AV-1959R: Abeta-targeting Anti-Alzheimer's Vaccine NCT06831812 AV-1959R (Abeta vaccine) Runs in: Australia · 1 site	PHASE1 other	COMPLETED	16	Nuravax, Inc. INDUSTRY	2026-09-15
An Insole and Ankle Device for Monitoring Cognitive Decline in Individuals at Risk for Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD) NCT07127133 Insole and ankle device Runs in: United States · 1 site	NA other	NOT_YET_RECRUITING	150	HealthPartners Institute OTHER	2026-09-15
The WeACT Program for Family Caregivers of People Living With Dementia NCT07342569 WeACT Runs in: United States · 1 site	NA other	NOT_YET_RECRUITING	40	University of South Florida OTHER	2026-09-15
Group Digital Gaming: Experiences of Older Adults Living With Dementia in an Activity for Cognitive Impairment NCT07541144 Group-Based Digital Gaming Runs in: United States · 1 site	NA other	COMPLETED	24	George Mason University OTHER	2026-09-15
Efficacy and Tolerability of Memantine in Frontotemporal Dementia (FTD) Patients NCT00200538 memantine Runs in: France · 1 site	PHASE2 symptomatic-cholinergic	COMPLETED	52	Nantes University Hospital OTHER	2026-09-14
Baclofen to Prevent Agitation in Alcohol Addicted Patients in ICU NCT02723383 BACLOFEN; PLACEBO Runs in: France · 18 sites	PHASE3 other	COMPLETED	314	Nantes University Hospital OTHER	2026-09-14
Water-based Activity to Enhance Recall in Veterans: A Randomized Clinical Trial NCT04296565 Usual Care; WATER+CT Runs in: United States · 1 site	PHASE4 other	COMPLETED	121	VA Office of Research and Development OTHER_GOV	2026-09-14
Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease NCT04639050 RO7126209; Placebo Runs in: Australia; Canada; Chile; Japan; Poland; South Korea; Spa... · 37 sites	PHASE1\|PHASE2 other	ACTIVE_NOT_RECRUITING	241	Hoffmann-La Roche INDUSTRY	2026-09-14

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry: ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file: 7,816
Source file: trials.csv (3.8 MB, 7816 rows)
Basis: Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

MINocyclinE to Reduce inflammation and blood-brain barrier leakage in small Vessel diseAse (MINERVA): A phase II, randomized, double-blind, placebo-controlled experimental medicine trial Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024 · score 88/100
Safety and efficacy of crenezumab in cognitively unimpaired carriers of the PSEN1Glu280Ala mutation at risk for autosomal-dominant Alzheimer's disease in Colombia (API ADAD Colombia Trial): a phase 2, randomised, double-blind, placebo-controlled trial The Lancet. Neurology, 2026 · score 86/100
Study of mirtazapine for agitated behaviours in dementia (SYMBAD): a randomised, double-blind, placebo-controlled trial Lancet (London, England), 2021 · score 86/100
Randomized, double-blind study of zervimesine in mild to moderate Alzheimer's disease Journal of Alzheimer's disease : JAD, 2026 · score 86/100
Efficacy assessment of an active tau immunotherapy in Alzheimer's disease patients with amyloid and tau pathology: a post hoc analysis of the "ADAMANT" randomised, placebo-controlled, double-blind, multi-centre, phase 2 clinical trial EBioMedicine, 2024 · score 85/100

All 162 studies on Clinical trials →